What dose of exendin 9-39 was administered to mice?
Best insight from top research papers
Exendin 9-39 was administered to mice at a dose of 216 nmol/kg .
Answers from top 5 papers
More filters
| Papers (5) | Insight |
|---|---|
| The provided paper does not mention the dose of exendin 9-39 administered to mice. | |
| The provided paper does not mention the administration of exendin 9-39 to mice. | |
| The paper does not mention the dose of exendin 9-39 administered to mice. | |
| The dose of Exendin-9-39 administered to mice was 216 nmol/kg. | |
10 Citations | The provided paper does not mention the dose of exendin 9-39 administered to mice. |
Related Questions
What is the dose of ibuprofen in mice as control group for anti inflammatory study?5 answersThe control group in a study on the effects of ibuprofen in mice for anti-inflammatory purposes received a dose of distilled water equivalent to the experimental group's ibuprofen dose. Specifically, in a study on Swiss albino mice, the control group received the same volume of distilled water as the experimental group's ibuprofen dose of 40 µg/g body weight per day for 6 weeks. This control group setup allowed for a comparison of the effects of chronic ibuprofen exposure on the small intestine mucosa without the direct influence of the drug itself, highlighting the impact of ibuprofen on the reduction of functional cell mass in the lining epithelium of the small intestine.
What is the optimal dosage of isoliquiritigenin for mouse models of disease?4 answersThe optimal dosage of isoliquiritigenin (ILG) for mouse models of disease varies depending on the specific condition being studied. In the context of Parkinson's disease (PD), studies have shown that ILG at a concentration of 20 mg/kg effectively reduced neurological deficits. Similarly, in a model of acute myocardial infarction (AMI), ILG administered intraperitoneally showed significant cardiac protection at a dosage that was effective in reducing myocardial oxidative stress and inflammation. Additionally, in a study focusing on neurodegenerative diseases, ILG at concentrations ranging from 0.5–5 µM demonstrated neuroprotective effects against glutamate-induced neuronal death. Therefore, the optimal dosage of ILG for mouse models of disease ranges from 20 mg/kg for PD to 0.5–5 µM for neurodegenerative conditions, highlighting the versatility of ILG in different disease models.
What is the typical range of mRNA when treating mice with mRNA-loaded LNPs?5 answersThe typical range of mRNA when treating mice with mRNA-loaded LNPs is between 200 to 500 nm.
What is the range of mRNA concentration when treating mice with mRNA-loaded LNPs?5 answersThe concentration of mRNA when treating mice with mRNA-loaded LNPs varies depending on the specific study. In one study, mRNA-LNPs containing up to 12.5μg of custom mCherry mRNA were delivered to mice. Another study used mRNA-LNPs with different cholesterol molar percentages, ranging from 10 mol% to 40 mol%. Additionally, the optimal formulation of mRNA-LNPs for targeting splenic DCs had a size range of 200 to 500 nm. However, the specific concentration of mRNA in these LNPs was not mentioned in the abstracts provided. To obtain the exact concentration of mRNA in the LNPs, further details from the full text papers would be required.
What is the optimal dose of human umbilical cord mesenchymal stem cells in mice?3 answersThe optimal dose of human umbilical cord mesenchymal stem cells (hUC-MSCs) in mice varies depending on the specific condition being treated. For subacute spinal cord injury (SCI) repair, a medium dose of 1 × 106 hUC-MSCs/kg was found to be as efficient as a high dose of 4 × 106 hUC-MSCs/kg in producing therapeutic outcomes. In the case of reproductive and developmental toxicity studies, the no-observed-adverse-effect levels (NOAELs) for hUC-MSCs were determined to be 8.5 × 106/kg for fertility and early embryonic development, 1.2 × 107/kg for maternal toxicity, and 2.4 × 107/kg for embryo-fetal development. In lupus mice, multiple infusions of hUC-MSCs at Weeks 12 and 16 resulted in a significantly higher number of primordial follicles compared to infusions at only Week 12. For food allergy therapy, intraperitoneal administration of hUC-MSCs combined with oral gavage of the culture medium showed antiallergic properties in mice with ovalbumin-induced food allergy. In a porcine-pancreatic-elastase-induced emphysema model, hUC-MSCs at doses of 3 × 106 and 107 cells/kg body weight improved emphysema severity.
How much is an exon?6 answers