What is an X-linked inheritence thrombophilia disorder?
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X-linked inheritance thrombophilia disorder refers to a genetic disorder that affects coagulation and is caused by abnormalities in anticoagulant factors or coagulation factors. It is associated with an increased risk of venous thromboembolism (VTE) and can manifest as deep vein thrombosis or pulmonary thromboembolism in young individuals, often with a positive family history of thrombosis . The genetic background of inherited thrombophilia differs between Caucasians and East Asians . Inherited thrombophilia is considered an intractable disease and is officially designated as such, with treatment being subsidized as a public expense . The association of inherited thrombophilia with pregnancy increases the risk of thromboembolic disease and various complications, including preeclampsia, recurrent miscarriage, intrauterine growth restriction, early detachment of placenta, and prematurity . Screening for inherited thrombophilia in young women is recommended in certain cases, such as a personal history of VTE or first-degree relatives with a history of high-risk thrombophilia .
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