What is replisome?
Best insight from top research papers
The replisome is a large multi-subunit assembly that carries out the process of DNA replication. It is composed of various proteins that work together to unwind the parental DNA and synthesize new daughter strands. The replisome is responsible for connecting the unwrapping of the parental DNA with the creation of new daughter strands. It moves along the DNA template, pulling the DNA towards it as replication progresses. The replisome is a dynamic and highly regulated machine that ensures faithful DNA replication. It is conserved across different organisms, including bacteria (Gras et al., 2021) and eukaryotes (Pellegrini, 2021). The structure and mechanisms of the replisome have been extensively studied in both bacteria and eukaryotes (Wilkinson et al., 2021; Claussin et al., 2021).
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| Papers (4) | Insight |
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| The paper provides information about the replisome, which is a multi-protein complex responsible for coordinating DNA unwinding and synthesis during DNA replication. | |
| The paper provides information on the structure and mechanisms of the central proteins that act directly at replication forks in bacteria and eukaryotes, but it does not explicitly define what a replisome is. | |
| The paper provides information about the replisome, which is a large and dynamic multi-protein machine responsible for eukaryotic DNA replication. | |
| The replisome is a large multi-subunit assembly that carries out the process of chromosome replication in Escherichia coli. |
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