What is the biodegradation mechanisms of carboxymethylcellulose in animals?
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The biodegradation mechanisms of carboxymethylcellulose (CMC) in animals involve various processes. Studies have shown that CMC can be completely absorbed and excreted without accumulation. Physical techniques, such as using nano-knives to cut the long chains of CMC, have been developed to break down the macromolecules. White-rot fungi have been found to degrade the cellulose matrix, producing enzymes that can hydrolyze CMC into oligosaccharides and sugar monomers. Enzymatic hydrolysis studies have identified specific endoglucanases that effectively degrade CMC into lower molecular weight fragments, with some enzymes being less inhibited by substituents. Additionally, enzyme technology has shown promise in efficiently degrading CMC accumulations under field conditions, with identified cellulases contributing to the degradation process.
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19 Citations | Carboxymethylcellulose biodegradation in animals involves hydrolytic breakdown of the main chain and macrophagal pinocytosis, leading to complete absorption and excretion without accumulation. |
4 Citations | Not addressed in the paper. |
Open access 01 Jan 2015 | Not addressed in the paper. |
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