What is the downstream process of cephalosporin production?
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The downstream process of cephalosporin production involves several steps. First, the production process of a dry cephalosporin C sodium salt includes nano-filtration concentration, drying using a centrifugal spray drier, and packaging . Another process involves cleaving the ester group of the compound to obtain ceftazidime, which can be crystallized directly as the pentahydrate or converted from the dihydrochloride form . An improved cephalosporin intermediate-GCLE is produced by chlorinating a raw material and then heating in vacuum for concentration and cyclization . Cephalosporin C can also be produced by cultivating a microorganism in a nutrient medium and using an organic source of sulfur . Additionally, a cephalosporin can be produced by reacting two compounds in the presence of boron trifluoride or a complex thereof . These processes involve various steps such as chlorination, crystallization, cyclization, and cultivation, depending on the specific cephalosporin being produced.
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| The downstream process of cephalosporin production is not mentioned in the provided information. | |
| The downstream process of cephalosporin production involves cleaving the ester group using aqueous hydrochloric acid and crystallizing the resulting ceftazidime as the pentahydrate. | |
| The downstream process of cephalosporin production includes nano-filtration concentration, drying in a centrifugal spray drier, and packaging. | |
| The provided information does not mention the downstream process of cephalosporin production. | |
| The downstream process of cephalosporin production involves chlorination of a raw material and subsequent vacuum heating concentration to obtain the final product. |
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