What is the effect of epigallocatechin gallate on the immune system?
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Epigallocatechin gallate (EGCG) has been found to have a significant effect on the immune system . It acts as a booster of the immune system, promoting its proper functioning and performance . EGCG has been shown to have antimutagenic effects and can protect against DNA damage induced by mutagens . It also has a reparatory effect on immunosuppression caused by carcinogenic compounds . In addition, EGCG exhibits immunomodulatory effects by inhibiting transcriptional factors, enhancing regulatory T cell generation, and modulating the activation and differentiation of immune cells . Furthermore, EGCG has been found to have anti-inflammatory effects by blocking NF-κB and NLRP3 inflammasome, inhibiting pro-inflammatory cytokine production, and reducing reactive oxygen and nitrogen species . Overall, EGCG shows promise as a potential therapeutic agent for immune-related diseases and cancer .
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| Papers (4) | Insight |
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| The paper mentions that epigallocatechin gallate, a type of polyphenol, can induce epigenetic changes in cells. However, the specific effect of epigallocatechin gallate on the immune system is not mentioned in the paper. | |
47 Citations | Epigallocatechin gallate (EGCG) enhances immune response by increasing activating receptors and downregulating inhibitory receptors. |
| The paper states that epigallocatechin gallate (EGCG) has a reparatory effect on immunosuppression induced by carcinogens and has a modulating effect on natural and adaptive immunity. | |
| The paper discusses the immune-boosting properties of epigallocatechin-3-gallate (EGCG) and catechin, but it does not specifically mention the effect of EGCG on the immune system. |
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