What is the specific molecular mechanism by which neutrophils recognize and engulf plastic particles?
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Neutrophils recognize and engulf plastic particles through a specific molecular mechanism involving the release of neutrophil extracellular traps (NETs) . Polystyrene nanoplastics (PS NPs) induce the formation of NETs, which involves reactive oxygen species, peptidyl arginine deiminase 4 (PAD4), and neutrophil elastase . Overexpression of PAD4 induced by PS NPs further mediates histone citrullination and chromatin depolymerization . This mechanism provides important information for the assessment of safety and immunotoxicity of plastic particles .
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13 Citations | The provided paper does not discuss the specific molecular mechanism by which neutrophils recognize and engulf plastic particles. |
| The specific molecular mechanism by which neutrophils recognize and engulf plastic particles is not mentioned in the provided paper. | |
6 Citations | The specific molecular mechanism by which neutrophils recognize and engulf plastic particles is not mentioned in the provided paper. The paper focuses on the induction of neutrophil extracellular traps (NETs) by polystyrene nanoplastics (PS NPs) and the involvement of reactive oxygen species, peptidyl arginine deiminase 4 (PAD4), and neutrophil elastase in this process. |
| The specific molecular mechanism by which neutrophils recognize and engulf plastic particles is not mentioned in the provided paper. The paper discusses the mechanism of phagocytosis in general, but does not specifically address neutrophils or plastic particles. | |
| The specific molecular mechanism by which neutrophils recognize and engulf plastic particles is not mentioned in the provided paper. |
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