What is the suitable range of polar and dispersive surface free energy for biomaterials for better cell adhesion?
Best insight from top research papers
The optimal range of surface free energy for biomaterials to enhance cell adhesion involves a balance between polar and dispersive components. Research suggests that a high surface free energy, particularly the polar component, promotes eukaryotic cell adhesion while hindering bacterial adhesion, thus minimizing infections . For restorative materials, a surface energy below 38 mJ/m² or above 123 mJ/m² is associated with reduced plaque accumulation . Furthermore, the critical surface energy for good adhesion is above 40 mJ/m², as seen in acrylic materials, while values below 30 mJ/m² indicate poor adhesion, as observed in BIS-GMA composites . Overall, maintaining a suitable balance between polar and dispersive surface free energy within these ranges can significantly impact cell adhesion on biomaterial surfaces, influencing their blood compatibility and interaction with various cell types .
Answers from top 5 papers
More filters
| Papers (5) | Insight |
|---|---|
Open access•Journal Article 39 Citations | The suitable range of polar and dispersive surface free energy for biomaterials is crucial for better cell adhesion, with lower values indicating reduced adhesion, as shown in the study. |
| The suitable range for polar surface energy is around 70 mJ m−2, and for dispersive surface energy, it varies with roughness ratio for enhanced cell adhesion on biomaterials. | |
22 Citations | The suitable range for biomaterials' surface free energy is above 40 mJ/m2 for good adhesion (acrylic resins) and below 30 mJ/m2 for poor adhesion (BIS-GMA composites). |
33 Citations | For enhanced cell adhesion, biomaterials should have high polar surface free energy and moderate dispersive surface free energy, as shown in the study on eukaryotes and prokaryotes. |
| The suitable range for biomaterials' surface free energy is between 38-123 mJ/m2. Lower than 38 mJ/m2 or higher than 123 mJ/m2 reduces plaque accumulation, aiding cell adhesion. |
Related Questions
What is the relationship between surface roughness and adhesion films?4 answersSurface roughness plays a crucial role in the adhesion of thin films. Research indicates that smoother surfaces exhibit more pronounced adhesion hysteresis, leading to a stronger adhesion force. The adhesion energy between rough surfaces, especially in microsystems, is primarily governed by dispersion interactions, with contact interactions or plastic deformations contributing minimally. Additionally, the root mean square gradient of surface roughness can significantly impact adhesive pressures between surfaces, regardless of the overall roughness. These findings highlight the intricate relationship between surface roughness and adhesion in thin films, emphasizing the importance of understanding and controlling surface topography for various applications in fields like nanotechnology, high-value manufacturing, and biomechanics.
What are the factors that affect the adhesion of paint?4 answersThe factors that affect the adhesion of paint include surface preparation of the substrate and coating, types and curing conditions of the glue used, and scoring of the coating around the dolly. Adhesion is also influenced by the nature of the polymer material and substrate surface properties, film thickness, internal stress, and conditions of the coating application and service. In addition, the presence of connector molecules reactive with the substrate surface can enhance adhesion to chemically inert polyolefins. Furthermore, the addition of specific additives, such as gadoleic acid, petroleum resin, clay, and cowhide cream, can strengthen paint adhesion.
How contact angle analysis could measure surface energy of materials?4 answersContact angle analysis is a technique used to measure the surface energy of materials. By determining the contact angle of a liquid droplet on a solid surface, information about the surface energy can be obtained. The contact angle is influenced by the intermolecular forces between the liquid and solid, which are related to the surface energy. Several factors can affect the accuracy of contact angle measurements, such as surface roughness and sample preparation. To obtain reliable data, it is important to control these factors and ensure quasi-equilibrium of the droplet on the surface. Different liquids can be used as test liquids to calculate the surface energy components, such as Lifshitz-van der Waals and Lewis acid/base components. Contact angle analysis can be applied to various materials, including mineral aggregates, dental materials, and hydrophilic solids. It provides valuable information for understanding interfacial behavior, such as protein adsorption and cell adhesion, and can contribute to the development of thermodynamic models for material interactions.
Why the surface adhesion energy is important?5 answersSurface adhesion energy is important because it determines the strength of the bond between two surfaces and ultimately affects their mechanical behavior and failure. Insufficient interfacial adhesion can lead to degradation and failure of multilayered devices, such as flexible organic photovoltaics (OPVs). Improving interfacial adhesion can enhance the mechanical reliability of these devices and prevent degradation induced by mechanical stress. Surface energy is also a significant parameter for characterizing particulate materials and is widely used in simulations of bulk behavior. Accurate determination of adhesion energies is crucial for understanding the adhesion between particles and substrates, which is important in various industries, including the mineral industry and the baking industry. Overall, surface adhesion energy plays a crucial role in the performance and reliability of various materials and devices.
Is High molecular weight hyaluronic acid good for adhesion to the mucosa?5 answersHigh molecular weight hyaluronic acid (HMW-HA) has been shown to attenuate the degree of endometrial fibrosis after endometrial damage, which may contribute to preventing the formation of intrauterine adhesions. HMW-HA can also be used for the reduction and/or prevention of the formation of post-surgical adhesions. In terms of adhesion to the mucosa, HMW-HA has been found to display comparable adhesion to Carbopol, a positive control, in in vitro studies. However, when formulated into microspheres, the adhesive properties of HMW-HA are reduced, although the microspheres still show decreased mucociliary clearance. Overall, HMW-HA has shown potential as a mucoadhesive polymer and may have applications in preventing adhesions and promoting wound healing in various contexts.
What is the suitable range of surface energy for biomaterials for better cell adhesion?5 answersThe suitable range of surface energy for biomaterials for better cell adhesion is moderate surface energy (Es ≈ 70 mJ m−2).