What is the toxicity of gentian violet in a topical animal model?
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Gentian violet has been used for various purposes in medicine, including as an antiseptic, antifungal agent, and blood additive. While there is no unambiguous evidence indicating the toxicity of gentian violet, some studies have reported potential toxic effects. In a study on mice, gentian violet was found to be a carcinogen, with a positive dose response for hepatocellular carcinoma in both males and females . It also showed toxic effects on growing chick embryos and depressed mitotic activities in mouse bone marrow . However, when used externally, no serious side effects have been reported . The ototoxic effect of gentian violet in the middle ear has also been warned by clinicians . Overall, while gentian violet has shown potential toxic effects in certain animal models, its toxicity in a topical animal model specifically is not explicitly mentioned in the provided abstracts.
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| Papers (5) | Insight |
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135 Citations | The paper does not provide information about the toxicity of gentian violet in a topical animal model. |
144 Citations | The provided paper does not mention the toxicity of gentian violet in a topical animal model. The paper focuses on the chronic toxicity and carcinogenicity of gentian violet in mice through dietary exposure. |
71 Citations | The paper does not provide information about the toxicity of gentian violet in a topical animal model. The paper primarily focuses on the genetic toxicity of gentian violet in bacterial and cytogenetic assays. |
3 Citations | The paper does not provide information about the toxicity of gentian violet in a topical animal model. |
| The paper does not provide information about the toxicity of gentian violet in a topical animal model. |
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