What kind of anti cancer properties does coffee have?
Best insight from top research papers
Coffee exhibits various anti-cancer properties attributed to its phytochemical composition. Compounds like kahweol, cafestol, and chlorogenic acids found in coffee have shown anti-cancer effects. Kahweol and cafestol have been reported to inhibit cell proliferation, induce apoptosis, and suppress epithelial-mesenchymal transition in renal cancer cells. Additionally, Robusta coffee extract has demonstrated anti-cancer activity in breast, colorectal, brain, and bone cancer cells by reducing cell viability, affecting cell cycle progression, inducing apoptosis, and inhibiting clonogenic capacity. The antioxidant and non-antioxidant properties of coffee compounds contribute to its potential as a functional beverage with cancer risk reduction benefits. Overall, the diverse phytochemical profile of coffee offers a promising avenue for utilizing coffee as a natural source of anti-cancer agents.
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| Papers (5) | Insight |
|---|---|
| Coffee exhibits antitumor effects on breast, colorectal, brain, and bone cancer cells by reducing viability, altering cell cycle, inducing apoptosis, and affecting mitochondrial function, as shown in the study. | |
| Coffee, rich in chlorogenic acids, exhibits anti-cancer effects by reducing inflammation and lowering the risk of certain cancers like endometrial and hepatocellular cancer, as suggested by epidemiological studies. | |
| Coffee contains phytochemicals with antioxidant, anti-inflammatory, antifibrotic, and anticancer properties. Recent studies show an inverse association between coffee consumption and various cancer types. | |
01 Jan 2021 | Coffee, particularly Lampung Robusta, shows anticancer potential. Specific fractions, like G, exhibit cytotoxicity against MCF-7 breast cancer cells, indicating the presence of compounds with anticancer properties. |
10 Citations | Coffee diterpenes kahweol acetate and cafestol exhibit anti-proliferative and anti-migratory properties in human renal cancer cells by inducing apoptosis, inhibiting EMT, and downregulating key signaling pathways. |
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