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Whate is the function of chrolide in deep eluctic solvent with ascorbic acid and betaine hydrochloride? 


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Choline chloride plays a crucial role in deep eutectic solvents (DES) with ascorbic acid and betaine hydrochloride by forming intermolecular hydrogen bonds. This interaction leads to the creation of a liquid-state DES that is clear and transparent at room temperature, showcasing stability and low environmental impact. The DES based on choline chloride, ascorbic acid, and betaine hydrochloride demonstrates the ability to act as a medium for various applications, including extracting, separating, and storing oxidation-prone substances, food additives, and daily chemicals. The presence of choline chloride in the DES contributes to its green chemistry characteristics, making it a sustainable and environmentally friendly solvent option .

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Choline chloride in deep eutectic solvents with ascorbic acid analogues contributes to forming glass-forming fluids with low melting points, comparable viscosities, and potential antibacterial properties, expanding the range of bio-derived DES.
Not addressed in the paper.
Chloride in Betaine hydrochloride-based Deep Eutectic Solvents aids in CO2 capturing, enhancing the thermophysical properties for sustainable and green media, as highlighted in the research.
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Related Questions

How Deep eutectic solvents being used as electrochemical sensor for antioxidants?4 answersDeep eutectic solvents (DESs) are being used as electrochemical sensors for antioxidants. These DESs provide a greater potential window, enhanced electrocatalytic performance, and corrosion protection of electrodes, resulting in better sensitivity and durability of the sensor. The electrochemical behavior of polyphenols in DESs has been explored, and a linear relationship between concentration and peak current intensity has been established, demonstrating the potential of DESs for polyphenol content quantitation. Furthermore, the antioxidant capacity of polyphenols can be modulated through the choice of DES components, indicating the potential for DESs to influence the antioxidant activity of polyphenols. DESs have also been used in the development of biosensors, offering improved biodegradability, lower toxicity, and the ability to solubilize a wide range of molecules, including analytes that are usually insoluble and difficult to quantify. Overall, DESs show promise as eco-friendly and efficient solvents for electrochemical sensing of antioxidants.
Does betaine have any protective effects on the liver?5 answersBetaine has been shown to have protective effects on the liver. Studies have demonstrated that betaine can protect against histopathological changes induced by ethanol in hepatic and duodenal tissues. Additionally, betaine has been found to alleviate liver injury caused by carbon tetrachloride (CCl4) by reducing serum levels of liver enzymes and oxidative stress markers. Betaine also ameliorates hepatic steatosis by inhibiting the interaction between FoxO6 and PPARγ, thereby suppressing lipogenic gene transcription. Furthermore, betaine administration has been shown to normalize the intrahepatic ratio of S-adenosylmethionine (SAM) to S-adenosylhomocysteine (SAH) and attenuate alcohol-induced liver damage, including steatosis. Finally, betaine supplementation has been found to alleviate high-fat diet-induced disruption of hepatic lipid and iron metabolism, potentially through the modification of CpG methylation on the promoter of lipogenic and iron-metabolic genes.
Does topical ascorbic acid have benefits for the skin?4 answersTopical ascorbic acid has benefits for the skin. It has antioxidant potential, whitening action, and plays an essential role in collagen synthesis and maintenance. However, ascorbic acid is chemically unstable and has poor skin permeability, which limits its effectiveness when applied topically. To overcome these challenges, derivative molecules and stabilization strategies have been explored. Studies have shown that ascorbic acid-loaded microneedles with an optimal amount of polyethyleneimine as an additive enhance ascorbic acid stability, improve skin penetration ability, and have antimicrobial properties. Furthermore, topical application of ascorbic acid and its derivatives has been found to improve skin firmness, hydration, elasticity, colorimetry of stains, and wound closure. However, more randomized clinical trials with standardized parameters and larger sample sizes are needed to further evaluate the efficacy of topical ascorbic acid.
What are the applications of deep eutectic solvents in the field of pharmaceuticals?5 answersDeep eutectic solvents (DESs) have various applications in the field of pharmaceuticals. They can be used for natural product extraction, drug delivery systems, and trace metal determination. DESs have high extraction rates in flavonoids and phenols, increasing the solubility of drugs in drug delivery systems. They can also effectively extract and pre-concentrate metals in trace metal determination. Additionally, DESs can be used as efficient and biodegradable solvents for the extraction of bioactive chemicals from plants or microorganisms. They are considered green and ecological solvents, providing a promising alternative to traditional methods. DESs have been shown to be efficient extraction media for phenolics, flavonoids, terpenes, saponins, and other natural plant ingredients. Overall, DESs offer a greener and more sustainable approach in the pharmaceutical industry, providing efficient extraction and delivery systems for bioactive compounds.
What is the effect of NaCl solvent on the extraction of Beta vulgaris?5 answersThe effect of NaCl solvent on the extraction of Beta vulgaris has been studied in several papers. It has been found that the diploid (2X) genotype of sugar beet showed higher growth performance compared to the tetraploid (4X) and triploid (3X) genotypes under salt stress conditions. Additionally, the Na+/H+ antiporter BνNHX1 in Beta vulgaris has been shown to play an important role in salinity tolerance, with its abundance increasing after salt treatments. However, the specific effect of NaCl solvent on the extraction of Beta vulgaris compounds such as betanin and betalain pigments has not been directly addressed in the provided abstracts.
Can betaine hcl heal gastritis ?1 answersБетаин HCl има потенциал да подпомогне абсорбцията на слабо основни лекарства, които проявяват рН-зависима разтворимост, когато се прилагат при хипохлорхидрични условия. Доказано е, че временно понижава стомашното рН при здрави доброволци с фармакологично индуцирана хипохлорхидрия. В проучване с дазатиниб, целенасочено противораково лекарство, едновременното приложение на бетаин HCl значително увеличава абсорбцията на дазатиниб при хипохлорхидрични състояния, обръщайки въздействието на хипохлорхидрията върху експозицията на лекарството. При кучета лечението с бетаин HCl понижава стомашното рН и намалява неговата променливост, докато лечението с фамотидин поддържа стомашното рН при по-високи стойности. Въпреки че е доказано, че бетаин HCl има антиоксидантни свойства и може да бъде полезен при лечение на гастрит и рак на стомаха, неговата специфична роля в лечението на гастрит не е пряко разгледана в предоставените резюмета.

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