scispace - formally typeset
Search or ask a question

Whole genome sequnce of black bone chicken 


Best insight from top research papers

Whole-genome sequencing data from various studies on black-bone chickens, including Muchuan, Jinhu, Rugao, Huangshan, and Xuefeng breeds, have provided valuable insights into the genetic characteristics of these unique chicken breeds. These studies have identified specific genetic features such as complex chromosomal rearrangements at the fibromelanosis (Fm) locus, mitochondrial DNA sequences, and gene expression profiles related to egg-laying performance and meat quality. The Fm locus on the 20th chromosome is crucial for melanin hyperpigmentation in black-bone chickens, with shared complex rearrangements among different breeds . Additionally, mitochondrial DNA sequencing has revealed the genetic composition and phylogenetic relationships of various black-bone chicken subspecies . These comprehensive genomic analyses contribute significantly to understanding the genetic distinctiveness and unique traits of black-bone chickens.

Answers from top 5 papers

More filters
Papers (5)Insight
The complete mitochondrial genome sequence of the Xuefeng black-boned chicken was reported, including 2 ribosomal RNA genes, 13 protein-coding genes, 22 transfer RNA genes, and a non-coding control region.
Not addressed in the paper.
The complete mitochondrial genome sequence of Jinhu Black-bone chicken was determined to be 16,785 bp, including 22 tRNA genes, 13 protein-coding genes, and 2 rRNA genes.
Not addressed in the paper.
Whole-genome sequencing of black-bone chicken breeds, including Kadaknath, reveals a complex chromosomal rearrangement at the fibromelanosis locus, shared among breeds, with unique selective sweep regions and protein-coding changes in Kadaknath.

Related Questions

Whole-Genome Regression and Prediction Methods Applied to Animal Breeding5 answersWhole-genome regression and prediction methods play a crucial role in animal breeding, enabling the estimation of genetic values for various traits. Traditional approaches like BLUP and GBLUP utilize relationship measures between individuals for prediction. Machine learning methods, such as Kernel Ridge Regression (KRR) optimized with a tree-structured Parzen estimator (TPE), have shown superior predictive abilities in genomic prediction studies. Comparatively evaluating different groups of supervised machine learning methods reveals that the classical linear mixed model and regularized regression methods remain strong contenders due to their competitive predictive performance, computational efficiency, and simplicity. Additionally, non-parameterized methods like Multivariate Adaptive Regression Splines (MARS) have been effective in genomic wide selection (GWS) analysis, particularly for traits with epistatic effects and varying heritability levels. These diverse methods collectively contribute to advancing animal breeding through accurate genomic predictions.
Whole exon sequencing5 answersWhole exome sequencing (WES) is a genetic testing method that analyzes the protein-coding regions of the genome to identify potential disease-causing variants. WES has been used in various contexts, including the diagnosis of prenatal and postnatal neurodevelopmental disorders (NDDs). It has shown a molecular diagnosis rate of 30% in NDD cases, with higher diagnostic yield when combined with copy number variant (CNV) analysis. WES has also been used in the identification of genetic etiologies of ultrasound abnormalities in deceased fetuses, with a diagnostic rate of 45.9% and the detection of previously unreported variants. In the field of foetal structural abnormalities, WES has been employed to improve diagnostic yield by evaluating variants, including introns, and has identified new candidate genes, particularly on chromosome X. Additionally, WES has played a role in the genomic detection and treatment selection for synchronous multiple primary lung cancer (sMPLC). Overall, WES has proven to be a valuable tool in genetic diagnosis and understanding the underlying causes of various conditions.
Whole genome sequencing breast cancer5 answersWhole-genome sequencing of breast cancer has provided valuable insights into the molecular characteristics of the disease and has led to advancements in personalized treatment options. Transcriptomic analysis and molecular subtyping have improved our understanding of breast cancer biology and enabled personalized treatment regimens. Whole-genome sequencing has also revealed the diversity of breast tumors and identified novel subgroups with distinct clinical outcomes. Additionally, whole-genome sequencing has been used to classify triple-negative breast cancers (TNBCs) and predict homologous-recombination-repair deficiency, providing independent prognostic information. Furthermore, deep whole-genome sequencing of breast cancer cell lines and patient-derived xenografts has identified novel genomic alterations and provided a comprehensive resource for studying these models. Overall, whole-genome sequencing has proven to be a valuable tool in understanding the genetic landscape of breast cancer and has the potential to improve clinical decision-making and treatment strategies.
Whole genome sequencing of sars5 answersWhole genome sequencing of SARS-CoV-2 has been a crucial tool in monitoring the pandemic and understanding its dynamics. Different protocols and sequencing technologies have been compared to determine their advantages and limitations. One study compared the outcomes of four different sequencing protocols using Illumina kits and found that miniaturized volumes showed comparable results to full volumes, reducing cost and library preparation time. Another study compared three different protocols using Illumina and Oxford Nanopore Technologies and found that the ARTIC and Midnight protocols were robust, cost-effective, and suitable for clinical environments. A cross-sequence technology benchmarking study compared five protocols and found that the ONT protocol and Illumina AmpliSeq protocol had the highest genome coverage, while the EasySeq protocol had the highest proportion of SARS-CoV-2 reads relative to background sequences. Additionally, a protocol using the Oxford Nanopore Rapid Barcoding library kit was developed for universal SARS-CoV-2 genome sequencing, allowing sequencing of low-titer virus samples and degraded RNA. Finally, a proof-of-concept study demonstrated the feasibility of conducting SARS-CoV-2 whole genome sequencing in a military maritime environment using miniaturized nanopore sequencing technology.
Whole exome sequencing illumina5 answersWhole exome sequencing using Illumina technology is a technique for sequencing all of the genes that code for functioning proteins in the genome. It is being used to identify mutations in families with suspected hereditary cancer syndromes where other testing methods have been unsuccessful. The accuracy of SNP calling in exome sequencing can be evaluated using high-throughput validation with Mendelian inheritance checking and SNP array data. This allows for the assessment of the quality of the derived SNPs and the comparison of different variant discovery tools. The goal is to identify the best variant caller(s) for clinical applications.
Whole genome sequencing in human genetic disease5 answersWhole genome sequencing (WGS) has revolutionized the field of human genetic disease research. WGS utilizes massively-parallel short-read DNA sequencing and genome assembly methods to rapidly search and analyze genomes on a large scale. It has become increasingly prevalent in detecting disease genetics, studying causative relations with cancers, and reconstructing human population history. WGS has applications in both mendelian and complex diseases, providing valuable insights into disease mechanisms and potential therapeutic targets. It has also played a significant role in cancer studies, regulatory variant analysis, predictive medicine, and precision medicine. However, there are challenges associated with WGS, including data analysis and interpretation. Despite these challenges, WGS has the potential to become a common medical practice, aiding in the diagnosis and treatment of genetic diseases.

See what other people are reading

What are maladaptive cognitive emotion regulation strategies?
5 answers
Maladaptive cognitive emotion regulation strategies refer to ineffective ways individuals manage their emotions, leading to negative outcomes. These strategies include expressive suppression, self-blame, catastrophizing, blaming others, and rumination. Research indicates that these maladaptive strategies are associated with various mental health issues such as posttraumatic stress disorder (PTSD), imposter syndrome among PhD candidates, and negative relationship conflict behaviors in the context of alcohol use problems. Maladaptive strategies like expressive suppression have been linked to higher PTSD symptoms in first responders, while PhD candidates experiencing imposter thoughts tend to use more maladaptive strategies like self-blame and catastrophizing. These strategies can have detrimental effects on well-being and mental health, highlighting the importance of understanding and addressing them effectively.
How can social well-being improve by a youth?
4 answers
Social well-being in youth can be enhanced through various means. Firstly, social support plays a crucial role in buffering the negative impacts of risk factors like delinquency and discrimination on mental well-being. Additionally, social skill training interventions are essential for improving social functioning, which is linked to emotional and social problems in youth. Furthermore, family social capital has been shown to directly relate to youth's social well-being, indicating that strong family connections can positively influence social well-being. Professionals working with youth also emphasize the importance of leisure activities in promoting social well-being, suggesting strategies to increase awareness and counteract barriers to participation in such activities. By fostering supportive relationships, enhancing social skills, strengthening family ties, and promoting leisure engagement, youth can significantly improve their social well-being.
Why use zinc salts in solid electrolyte preparation.?
4 answers
Zinc salts are utilized in solid electrolyte preparation due to their significant impact on enhancing the ionic conductivity, structure, and phase behavior of the electrolytes. Different zinc salts, such as zinc acetate, zinc sulphate, and zinc triflate, have been studied for their effects on the mechanical properties and stability of the solid electrolytes. Zinc salts play a crucial role in improving the ionic conductivity of the solid electrolytes, with the addition of zinc acetate leading to a maximum conductivity of 2.10 mS cm-1. Additionally, the use of zinc salts like zinc chloride, zinc bromide, and zinc acetate in a ternary system has been shown to result in a solid electrolyte with high ionic conductivity and improved battery performance. Overall, the incorporation of zinc salts in solid electrolytes is essential for achieving better performance and stability in zinc-based batteries.
What pollutants are used in 3D printer filaments?
5 answers
Various pollutants are present in 3D printer filaments, including volatile organic compounds (VOCs) and particulate matter. Studies have highlighted the emission of VOCs like lactide, acetone, and formaldehyde during filament extrusion and 3D printing processes. Additionally, particulate emissions, especially nanoparticles below 50 nm in diameter, are released during printing, with higher concentrations observed at temperatures above 200°C. These emissions pose health risks, as exposure to nanoparticles through inhalation has been linked to adverse health outcomes. Furthermore, the emission of solid particles, particularly during printing, can lead to throat irritation, cardiovascular issues, and stroke, emphasizing the importance of proper ventilation and air purification in spaces with multiple printers.
1.How does the quality of ESG disclosure affect a company's financial performance?
5 answers
The quality of Environmental, Social, and Governance (ESG) disclosure significantly impacts a company's financial performance. Research indicates that firms with superior ESG performance tend to have lower debt financing and easier access to equity funding via stock markets. Moreover, ESG performance can enhance corporate performance across all life cycle stages, especially during growth stages, with financial risk mediating this relationship. Additionally, ESG disclosure can influence a company's cost of debt financing in two opposite directions, with greater disclosure leading to both lower and higher costs depending on growth opportunities and prospective risk. Furthermore, the joint effect of ESG disclosure and green innovation positively affects financial performance, emphasizing the financial impact of sustainability tools. Overall, better ESG performance is associated with reduced financial irregularities, with stakeholder attention further strengthening this relationship.
What is meant by Bossy attitude, an indicator for measuring autocratic leadership?
5 answers
A bossy attitude, often associated with autocratic leadership, refers to a domineering and controlling demeanor exhibited by superiors towards subordinates, leading to negative consequences. This behavior is akin to abusive supervision, characterized by long-term, systematic negative actions by bosses towards their employees. An indicator for measuring autocratic leadership can be seen in the tyrannical management approach, where leaders exhibit negative feelings and attitudes, causing adverse effects on the organization and its employees. This autocratic style of management is detrimental to organizational health and employee well-being, resulting in despondency, demotivation, and lack of trust among the workforce. Such behaviors can be detected through various sensors and indicators, like attitude sensor devices based on MEMS technology, which can measure deviations from a reference orientation.
What are the specific mechanisms through which T. harzianum affects the quality of citrus fruits?
5 answers
Trichoderma harzianum influences the quality of citrus fruits through various mechanisms. Firstly, T. harzianum enhances plant growth, physiology, and fruit quality by improving seedling morphology, nutrient content, and chlorophyll levels. Secondly, T. harzianum contributes to biocontrol mechanisms, particularly through mycoparasitism, antibiosis, and induced systemic resistance, which collectively enhance fruit quality. Additionally, the application of T. harzianum in citrus cultivation can lead to a reduction in citric acid levels, impacting the sugar-acid ratio and ultimately improving fruit sweetness. These combined effects highlight the multifaceted role of T. harzianum in enhancing citrus fruit quality through growth promotion, biocontrol mechanisms, and modulation of fruit metabolites.
Who wrote about “infrastructural theory of change”?
5 answers
Staffan Furusten discussed the "infrastructural theory of change" in his book, emphasizing how managers' decision-making is influenced by institutional constraints in their environment, impacting organizational change processes. Additionally, researchers have highlighted the importance of understanding the interplay between agency and social structure in organizational change studies, with Strong Structuration Theory (SST) offering a comprehensive framework that balances these perspectives effectively. Furusten's work sheds light on the challenges organizations face in resisting institutional pressures globally, leading to increasing similarities among organizations of varying sizes and sectors. By incorporating insights from both Furusten's analysis of institutional constraints and the application of SST in change research, a more nuanced understanding of organizational change processes and the role of infrastructure in shaping them emerges.
How coating carbon-based works? xps?
5 answers
Coating carbon-based materials involves various techniques and applications as discussed in the provided contexts. For instance, alcohol-based conductive paints containing graphite, carbon black, graphene, and other materials were developed for electromagnetic interference shielding, offering efficient EMI-shielding performance. Additionally, carbon-based films with excellent friction-reducing and antiwear abilities can be formed in situ from the degradation of poly-α-olefin oil on specific coatings, resulting in low friction coefficients and wear rates. Moreover, carbon-based coatings have been successfully applied in mechanical machining of wood-based materials, enhancing tool durability and wear resistance. These examples highlight the versatility and effectiveness of carbon-based coatings in various industrial applications, showcasing their potential in improving performance and durability. Unfortunately, there is no specific mention of XPS (X-ray photoelectron spectroscopy) in the provided contexts.
Is time positively correlated with current in microbial fuel cell?
5 answers
Time in microbial fuel cells (MFCs) can be positively correlated with current under certain conditions. Research has shown that the microbial density and electricity produced at the cathode in MFCs exhibit a positive correlation over time. Additionally, a study on a Matlab-based MFC model revealed that variations in initial substrate and electron acceptor concentrations can impact the power output time, indicating a relationship between time and power generation in MFCs. Furthermore, the use of current interruption methods in MFCs can monitor electrochemical changes, including variations in internal resistance, over time during operation. Therefore, time can indeed be positively correlated with current in microbial fuel cells, influenced by factors such as microbial activity, substrate concentrations, and operational conditions.
What is synthesis of cyclophane-braced peptide macrocycles via palladium-catalysed intramolecular sp3 C−H arylation?
5 answers
The synthesis of cyclophane-braced peptide macrocycles via palladium-catalyzed intramolecular sp3 C−H arylation involves utilizing transition-metal-catalyzed C−H activation strategies to create unique peptide topologies. Recent advancements in C−H activation, particularly C−H arylation, have shown significant progress in this area. By cross-linking aromatic side chains of Trp, His, and Tyr residues with aryl linkers through copper-catalyzed double heteroatom-arylation reactions, diverse assemblies of tension-bearable multijoint braces can be formed to modulate the backbone conformation of peptides, leading to previously inaccessible conformational space. Additionally, the direct synthesis of polyketide and polypeptide macrocycles via transition-metal-catalyzed C−H bond activation strategies has been explored, showcasing the potential for innovative approaches in macrocyclization.