Showing papers on "Aphanamixis published in 2015"
TL;DR: A total of 14 new diterpene dimers with four known homologous compounds were isolated from the root barks of Aphanamixis grandifolia, and all the compounds exhibited significant inhibition of lipopolysaccharide-induced nitric oxide production in RAW264.
Abstract: A total of 14 new diterpene dimers, aphanamenes C–P (1–14), with four known homologous compounds were isolated from the root barks of Aphanamixis grandifolia Bl. The structures of these compounds were elucidated by spectroscopic analyses, and their absolute configurations were determined using the CD exciton chirality method. In addition, all the compounds exhibited significant inhibition of lipopolysaccharide-induced nitric oxide production in RAW264.7 macrophages, with IC50 values between 7.75 and 38.23 μM.
13 citations
TL;DR: Aphanamenes C (Ia), D (IIb), E (Ib), F (IIa), G (IIIa), H (IVb), I (IIIb), J (IVa), K (Ic), L (IId), M (Id), N (IIc), O (IIId) and P (IVc) are isolated as discussed by the authors.
Abstract: Aphanamenes C (Ia), D (IIb), E (Ib), F (IIa), G (IIIa), H (IVb), I (IIIb), J (IVa), K (Ic), L (IId), M (Id), N (IIc), O (IIId) and P (IVc) are isolated.
1 citations
TL;DR: In this paper, the exact configuration of 1 was determined by comparison the experimental and calculated electronic circular dichroism (ECD) spectra of Aphanamixis grandifolia.
Abstract: Five new limonoids, aphagranols D–H (1–5, resp.), were isolated from the EtOH extract of the fruits of Aphanamixis grandifolia by chromatographic methods. Their structures were established on the basis of extensive spectroscopic analyses. The absolute configuration of 1 was determined by comparison the experimental and calculated electronic circular dichroism (ECD) spectra. All of the isolates were evaluated for insecticidal activities.
1 citations