Showing papers on "Biflavonoid published in 1991"
TL;DR: The antihepatotoxic action of kolaviron was clearly demonstrated in the model of hepatitis employed in this study, as well as causing significant increases in activities of the serum enzymes assessed.
Abstract: Male rats (200–220 g) were treated with toxic doses of carbon tetrachloride (2 mL/kg per day i.p., for 3 days) to induce liver damage. Another group of rats received kolaviron, a biflavonoid extract from seeds of Garcinia kola (500 mg/kg, i.p.) 1 h prior to receiving carbon tetrachloride. Tests for liver function were performed on all animals. The activities of glutamic oxaloacetatetransaminase (GOT), glutamic pyruvate transaminase (GPT), sorbitol dehydrogenase (SDH) and glutamic dehydrogenase (GLDH) in serum were determined, as were the concentrations of hepatic glutathione (GSH) and triglyceride in liver. Hepatic lipid peroxidation was assessed by measuring hepatic malondialdehyde (MDA) formation in the liver. Carbon tetrachloride induced marked depletion of GSH and increased the formation of MDA and triglyceride in the liver, as well as causing significant increases in activities of the serum enzymes assessed. Pretreatment with kolaviron significantly attentuated all the alterations caused by carbon tetrachloride. The antihepatotoxic action of kolaviron was clearly demonstrated in the model of hepatitis employed in this study.
58 citations
TL;DR: Amentoflavone derivatives were prepared by catalytic coupling of 8-flavone-boronic acids with iodoflavones as discussed by the authors, and 3-Arylflavones, as biflavonoid synthon, are accessible by the method.
44 citations
TL;DR: It was found that the major leaf flavonoids are flavonol glycosides (in 68%) and flavone C-glycoside (in 48% of taxa) and this combination of characters distinguishers this subfamily from the Barbacenioideae.
24 citations
TL;DR: An important chemical factor which may reduce the activities of flavonoid class of inhibitors for tumor promotion was indicated.
21 citations
TL;DR: The macrocyclic biflavonoid Bartramiaflavone, which consists of two equilibrating cyclo-oxo tautomers has been isolated from Bartrammia pomiformis as discussed by the authors.
10 citations
TL;DR: In this paper, the flavonoid glycosides and the biflavonoids of cypress leaves have been separted by means of high-performance thin-layer chromatography with quantitation by densitometry.
Abstract: The flavonoid glycosides and the biflavonoids of cypress leaves have been separted by means of high-performance thin-layer chromatography with quantitation by densitometry. Some flavonoid glycosides and biflavonoids have been identified, other than from their chromatographic characteristics, by means of UV spectra recorded directly on the layer. Different clones, resistant and susceptible to cypress canker, have been analyzed; some differences between these two classes of trees have been found in their biflavonoid content.
6 citations