Showing papers on "Chrysanthemum indicum published in 2007"

Search for bioactive constituents from several medicinal foods : hepatoprotective, antidiabetic, and antiallergic activities

Abstract: In the course of our characterization studies on bioactive constituents from medicinal herbs, several medicinal foods and their constituents were found to show the following biological activities: (1) hepatoprotective sesquiterpenes from Zedoariae Rhizoma (2) α-glucosidase and aldose reductase inhibitors form Salacia spices and the flowers of Chrysanthemum indicum, and (3) anti-allergic and antiinflammatory diaryloheptanoids from the barks of Myrica rubra and Acer nikoense.

Isolation of Acetylcholinesterase Inhibitors from the Flowers of Chrysanthemum indicum Linne

Abstract: There is significant interest in finding new sources of acetylcholinesterase (AChE) inhibitors for use in treating Alzheimer's disease, since only a few AChE inhibitors are available for clinical use, such as galanthamine, physostigmine, and tacrine. The ethanol extract of Chrysanthemum indicum Linne flowers was analyzed and found to markedly decrease AChE activity. Acaciin and acacetin-7-O-B-D-galactopyranoside were identified as the active compounds responsible for the AChE inhibition by using an activity-guided fractionation strategy. The relationship between structure and activity for five flavonoids (acaciin,acacetin-7-O-B-D-galactopyranoside , luteolin, and two other commercially available flavonoids, i.e., apigenin and acacetin) was also investigated, revealing that the presence of methoxy groups at C-4' in the B ring and a sugar at O-7 in ring A appear to be essential for the inhibition of AChE.

Optimization of Extraction Conditions for Hot Water Extracts from Chrysanthemum indicum L. by Response Surface Methodology

Abstract: Extraction conditions were optimized using response surface methodology for preparing high-quality, hot water extracts from cultivated Chrysanthemum indicum L. petals. A fractional factorial design was applied to investigate the effects of added sample ratio (), extraction temperature () and extraction time () variables on extract properties, such as, soluble solid contents (), sugar content (), ?E (), turbidity (), total phenol () and DPPH (). Second-order models were employed to generate a 3-dimensional response surface for dependent variables and their coefficients of determination () ranged from 0.84080.9914. The range of optimum conditions at extraction for maximize characteristics of hot water extracts was 2.32.7 g and 9.211.2 hr.

Separation and purification of flavonoids from chrysanthemum indicum with macroporous resin

Abstract: Objective A method for separation and purification of flavonoids from C. indicum with macroporous resin was studied. Method By using C. indicum in Guizhou as the materials and with the content and recovery rate of flavonoids as indexes, the static and dynamic adsorption tests were employed to investigated effects and affective factors of separation and purification of flavonoids from C. indicum with macroporous resin. Result Results show that the static adsorption capacity of AB-8 type resin was 114.65 mg x g(-1), the static elution ratio were 94.9%, the dynamic adsorption capacity of AB-8 type resin was 94.5 mg x g(-1), the recovery rate was more than 92.6% and the purity of flavonoids was more than 90%. AB-8 type resin is the best for separating and purificating C. indicum in flavonoids. Conclusion The optimum conditions is AB-8 type macroporous resin, 70% alcohol as the eluant and 2 to approximately 3 times volume of the resin as the eluant volume, the ratio of flavonoids to the volume of the resin as 1:10.6, concentration of flavonoids of sample as 19.8 mg x mL(-1) and current velocity as 2 to approximately 3 mL x min(-1), pH value of sample as 4 to approximately 5. [Key words]' macroporous resin; Chrysanthemum indicum; flavonoids; separation; purification

Method of oriental herb body-heating-cream

Abstract: A method for preparing an oriental herb material is provided to obtain an oriental sweat constituent concentrate capable of radiating far-infrared rays under high temperature condition such as a sauna, promoting discharge of the sweat and showing effect permeation into skin, thereby being used as a raw material for an oriental body cream. The method for preparing an oriental herb material comprises the steps of: (a) selecting two herbs from the group consisting of Mentha arvensis var. piperascens, clove, Teucrium veronicoides, camphor, Persicae Semen and Armenicae Semen; (b) selecting two herbs from the group consisting of Aconitum ciliare Decaisne, Zingiber officinale Roscoe, Pueraria flos, and Aconitum carmichaeli Debeaux; (c) selecting 10 herbs from the group consisting of Cnidium officinale, Angelicae Gigantis Radix, Paeonia lactiflora Pallas, Cortex Phellodendri, Artemisia nakai, Zanthoxylum piperitum, Cinnamomi cortex, fraxini cortex, Saururus chinensis, Pleuropterus multflorus, Glycyrrhiza uralensis, Carthamus tinctorius, Chrysanthemum indicum, Angelica dahurica(Fischer) BENTHAM et HOOKER, Amomi Cardamomi Fructus, Cuscuta chinensis Lamark., Chestnut inner bark, bombyx mori, ginseng, green tea leaves, pine needles, pumpkin, apricot, lemon, fig, papaya, Paeonia Suffruticosa Andrews, Coix lachrymajobi var. mayuen and chrysanthemum; and (d) extracting the selected herbs with a surfactant for food such as a sugar ester and a sorbitan with an extraction solvent such as ethanol and glycerin at low temperature under reduced pressure. To prepare the body cream, a ceramic powder or an aqueous solution thereof or a colloidal solution thereof having far-infrared rays radiating capacity of more than 92% and a body cream are mixed in a ratio of 5-20%:0.5-1.5%:78.5-94.5%.

Method of preparing doenjang, a korean soybean paste, containing extract of chrysanthemum indicum linne and the chrysanthemum doenjang obtained from the method

Abstract: A method of manufacturing soybean paste by addition of chrysanthemum extract during the manufacture of soybean paste is provided to obtain soybean paste having antithrombotic activity and antioxidant activity First, 1L chrysanthemum extract is mixed with 1kg soybeans and heated to obtain fermented soybeans Secondly, fermented soybeans are aged and ground Then, 1kg fermented soybean powder is mixed with 100 to 300ml chrysanthemum extract and aged The chrysanthemum extract is a hot water extract of flowers of live chrysanthemum or dried chrysanthemum

Supercritical CO_2 Extraction of Essential Oil from the Flower of Chrysanthemum indicum Lamb

Abstract: The extraction and isolation conditions of essential oil were studied using the flower of Chrysanthemum indicum Lamb as the starting material with supercritical CO2 process.Influences of extraction temperature,extraction pressure,and extraction time on the content of essential oil were investigated,and suitable conditions were determined based on the single-factor tests.They were as follows:extraction temperature 35℃,separation temperature 30 ℃,extraction time 90 min,extraction pressure 25 MPa and CO2 flow 30 kg/h.The yield of essentical oil was 9.7 % under above conditions.Using GC-MS analysis,43 compounds were identified.They were mainly terpen compounds and their oxides,hydrocarbon compounds,ester compounds and so on.

Decoction made from cortex moutan, chrysanthemum indicum and so on

Abstract: Disclosed is a medicinal decoction for treating hypertension and arteriosclerosis, which is prepared mainly from bark of peony root, wild chrysanthemum flower, eupatene, silver flower stem, spatholobus stem, abalone shell and pumpkin peel.

Effects of Hagocho (Prunella vulgaris L.), Gamgook (Chrysanthemum indicum L.) and Galgeun (Pueraria Radix) on Plasma Lipid Compositin and Histological Consideration in Hyperlipidemic Rat

Abstract: Effects of prunella vulgaris L., chrysanthemum indicum L. and pueraria Radix on plasma lipid composition and histological consideration were investigated in hyperlipidemic rats. Concentration of plasma showed a tendence to decrease in prunella vulgaris L., chrysanthemum indicum L. and pueraria Radix treatment groups. However these values were showed not significantly different from control group. Concentration of plasma FFA in prunella vulgaris L., chrysanthemum indicum L. and pueraria Radix treatment groups showed a lower values compared to control group and concentration of plasma FFA of prunella vulgaris L. and pueraria Radix treatment group showed a lower values than prunella vulgaris L. and chrysanthemum indicum L. treatment group. Concentration of plasma glucose and triglyceride showed a tendence to decrease in prunella vulgaris L., chrysanthemum indicum L. and pueraria Radix treatment groups. However plasma glucose values showed not significantly different from control group. Plasma total cholesterol concentration showed a low and HDL-cholesterol concentration showed a high in prunella vulgaris L. and pueraria Radix treatment group. However LDL-cholesterol concentrations were not significantly different in treatment groups. Histological consideration of heart, liver and kidney in prunella vulgaris L. and pueraria Radix treatment groups showed a good features in fat accumulation condition than those of other treatment groups. However in the condition of high fat accumulation in tissues, heart, liver and kidney were showed a slight congestion and a bashed cell nucleus.

Effect of total flavonoids of Chrysanthemum indicum on TRAIL,TNF-α expression of synovial tissue from adjuvant arthritis rats in vivo

Abstract: Aim To investigate the effect of total flavonoids of Chrysanthemum indicum on proliferation of synoviocytes and TRAIL/TNF-α expression of synovial tissue with adjuvant arthritis ratsMethods SD rats were divided randomly into six groups including normol,model,TFC(84,168,336 mg·kg-1)and control drug Tripterygium glycosides(30 mg·kg-1)groupsAdjuvant arthritis rat model was induced by a single intradermal injection of 01 ml of the complete Freund's adjuvant into the the right hind feet pads of the SD ratsThe proliferation of synoviocyte was measured by MTT;The expression of TRAIL and TNF-α on synovial tissue were detected by means of immunofluorescenceResults TFC was shown to suppress the excessive synoviocyte proliferation;The expression of TRAIL was lower in model group than that of the normal groupTFC can increase the expression of TRAIL protein;The contrary to TNF-α proteinConclusions TRAIL play a role in the development of AATFC can increase the lower expression of TRAIL protein,that maybe one of the mechanisms of TFC improvement AA

Induction of apoptosis by extract of total flavonoids of chrysanthemum indicum on adjuvant arthritis synovial cells

Abstract: Objective To study the effect of the extract of total flavonoids of chrysanthemum indicum(TFC) on adjuvant arthritis synovial cells. Methods 0.1ml of the complete Freund's adjuvant was subcutaneously injected into the right hind feet pads of the SD rats.24 days after immunity synovial cells in knee joint were treated with TFC and inhibition of proliferation was measured with MTT assay.DNA fragmentations were analyzed with DNA gel electrophoresis.Fluorescence staining of Hoechst 33258 to observe apoptotic body.Results The IC_50 of TFC on synovial cells was 112mg/L.DNA gel electrophoresis showed ladder-like strap.Apoptotic bodies were observed by Hoechst 33258.Conclusion TFC can inhibit proliferation and induce apoptosis in synovial cells,and exerts therapeutical effect on rheumstoid arthritis.