Showing papers on "Delta wave published in 1979"
TL;DR: Results of this study indicate that the reduction of SWS with flurazepam during the initial drug nights is due primarily to the reduction in delta amplitude, but, with continued use, the decrease in delta count also contributes to the decreases in stage 4 sleep.
37 citations
TL;DR: Analysis of sleep effects of flurazepam hydrochloride on four normal subjects confirmed that this drug substantially suppresses both REM and stage 4 sleep, and suggests that sedative-hypnotics increase total sleep time by slowing the metabolic processes of sleep so that a longer sleep duration is required for the same biological effects.
Abstract: • Analysis of sleep effects of flurazepam hydrochloride on four normal subjects confirmed that this drug substantially suppresses both REM and stage 4 sleep. Computer analysis disclosed that delta wave amplitude was greatly reduced by flurazepam. However, low density delta wave activity (ie, stage 2 sleep, which was increased in duration beyond the reduction in stage 4), permitted the number of delta waves and the time they occupied per night to remain at baseline levels. This finding suggests that sedative-hypnotics increase total sleep time by slowing the metabolic processes of sleep so that a longer sleep duration is required for the same biological effects. New observations on the induction times of REM and stage 4 effects are also presented. In general, the distortions in sleep EEG produced by flurazepam qualitatively resemble, but are quantitatively greater than, those produced by barbiturates in equivalent hypnotic doses.
28 citations
TL;DR: 2 patients with hypoparathyroidism, one idiopathic and the other pseudoform, were studied by overnight polygraphic recording of the sleep EEG and related activities before and after start of treatment to investigate their sleep EEG patterns and states, showing findings suggestive of a possible disorder of the desynchronizing mechanism of the brain stem.
Abstract: 2 patients with hypoparathyroidism, one idiopathic and the other pseudoform, were studied by overnight polygraphic recording of the sleep EEG and related activities before and after start of treatment
4 citations
01 Jan 1979
4 citations
TL;DR: A 20 min period of diffuse brain stimulation, administered just before sleep onset in 16 human subjects, appeared to alter significantly the first sleep cycle of the succeeding sleep.