Showing papers on "Karanjin published in 2016"
26 Apr 2016
TL;DR: In this paper, the optimal geometry of karanjin has been determined by a density functional theory and compared with experimental values, which are in excellent agreement with the optimized geometry of the kanjin compound, and the potency of the compound against pathogenic indicators was evaluated and confirmed by Raman scattering and field emission scanning electron microscopy imaging.
Abstract: Pongamia pinnata, popularly referred to as Karanj, is a multipurpose legume well known for its traditional and pharmacological properties with an efficient remedy for human health problems. Karanjin, a furanoflavonoid (3-methoxy-2-phenylfuro [2,3-h] chromen-4-one), is the main constituent of Karanj seeds with important biological attributes. The present investigation was aimed at standardizing a process for the isolation of karanjin from seed oil with an emphasis on achieving a higher yield of the pure compound. Structural elucidation and characterization were carried out via HRMS, Fourier transform infrared spectroscopy, X-rays diffraction, NMR, Raman spectroscopy, and thermogravimetric studies. The optimized geometry of the karanjin compound has been determined by a density functional theory and compared with experimental values, which are in excellent agreement. The potency of karanjin against pathogenic indicators was evaluated and confirmed by Raman scattering and field emission scanning electron microscopy imaging. The physicochemical parameters of karanjin were determined by in silico drug likeness properties, and molecular docking was also performed, which revealed the potential of karanjin as a highly functionalized and medicinally useful compound. From the docked conformations, the carbonyl group, 3-methoxy group, and oxygen atom in the C ring of the karanjin molecule were found to be biologically important for hydrogen bond formation with common bacterial enzymes involved in fatty acid biosynthesis. The mode of antibacterial action of karanjin revealed the complex patterns of probable cell wall disruption. This is the first report with regard to karanjin characterization and theoretical calculations of a density functional theory and its utility as a potential pharmacophore depicting an antibacterial property using Raman spectroscopy and docking studies.
9 citations
TL;DR: The overall best performance of insecticides against whitefly was recorded in imidacloprid treated plots with lowest mean population of whitefly followed by karanjin and azadirachtin.
Abstract: The field experiment was carried out in the pre-kharif season of 2013 at Bidhan Chandra Krishi Viswavidyalaya, Kalyani, Nadia, West Bengal, India to evaluate the efficacy of different bio-pesticides against sucking pests of okra. The experiment was laid out in randomized complete block design with three replications for each treatment. The treatments viz. annonin 1% EC, karanjin 2% EC, Azadirachtin 1% EC, Metarrhizium anisopliae, Verticillium lecanii , Beauveria bassiana , Bacillus thuringiensis var Kurstaki, spinosad 45 % SC and imidacloprid 17.8% SL were applied at 15 days interval starting from seedling stage when whitefly and jassid infestation started. Results revealed that the overall best performance of insecticides against whitefly was recorded in imidacloprid treated plots with lowest mean population of whitefly (3.91 whitefly/15 leaves) followed by karanjin (4.16 whitefly/15 leaves) and azadirachtin (5.16 whitefly/15 leaves while the order of efficacy aginst jassid were imidacloprid (15.27 jassids/15 leaves) > karanjin (33.91jassids/15leaves)>azadirachtin(40.38jassids/15leaves). Effectiveness of test insecticides on the yield of okra wasspinosad>Bt>B. bassiana>azadirachtin>imidacloprid>annonin>karanjin>M. anisopliae.
6 citations
Patent•
22 Jul 2016
TL;DR: In this article, the authors describe a cosmetic ingredient that consists of a solution of at least one extract of karanja oil comprising pongamol (CAS 484-33-3) and karanjin(CAS 521-88-0) in one solvent chosen from the group of diesters having the following formula (I): n is between 0 and 19; R and R', which may be identical or different, are chosen from a group of alkyls derived from a linear or branched alcohol of empirical formula C x H 2x
Abstract: [0001] The invention relates to a cosmetic ingredient, characterized in that it consists of a solution of at least one extract of karanja oil comprising pongamol (CAS 484-33-3) and karanjin (CAS 521-88-0) in at least one solvent chosen from the group of diesters having the following formula (I), or mixtures thereof: in which formula (I): n is between 0 and 19; R and R', which may be identical or different, are chosen from the group of alkyls derived from a linear or branched alcohol of empirical formula C x H 2x+2 O before esterification, x being between 1 and 30, preferentially between 1 and 20, preferentially between 1 and 10. R" is either a hydrogen atom or a C 1 -C 3 alkyl group. [0002] The invention also relates to a selected precipitation process, to a cosmetic formulation and also to the uses thereof.
1 citations