Showing papers on "Oxazolidine published in 1986"

Process for preparing substituted phenol ethers via oxazolidine-structure intermediates

Abstract: Phenol ethers such as 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-[(1-methylethyl)amino]-2-propanol, otherwise known as betaxolol, of formula: ##STR1## are prepared from p-hydroxyphenethyl alcohol by first reacting at the phenolic group, with epichlorohydrin followed by isopropylamine, to prepare the required secondary amine-hydroxy side chain. Protection of the alcoholic group is not required during these steps. Then the secondary amine-alcohol group is protected by reaction with a suitable aldehyde such as benzaldehyde to form an oxazolidine ring protectant while the alcohol chain is elaborated. The oxazolidine ring protectant is removed by simple acid hydrolysis.

Herbicidal oxazolidines and methods of use

Abstract: An oxazolidine having the formula ##STR1## wherein X, Y, X' and Y' are the same or different and are selected from the group consisting of hydrogen, chloro, bromo, fluoro, trifluoromethyl, m-trifluoromethylphenoxy, methyl, methylthio, methoxy, cyano, nitro and methylsulfonyl; and R is selected from the group consisting of methyl ethyl, chloromethyl and hydroxy methyl.

Resin coating composition

Abstract: A resin coating composition characterized by containing as its resin binder an epoxy resin derivative having an oxazolidine ring functional group of the formula ##STR1## where R 1 is an alkylene group of 2 to 6 carbon atoms, R 2 and R 3 are each hydrogen or methyl, and R 4 and R 5 are each a residue of aldehyde or ketone.

Urethane sealant having improved heat resistance

Abstract: PURPOSE:The titled sealant of one-pack type suitable for surrounding parts of automobile engine, etc., having improved elasticity, adhesiveness, cold resistance, etc., obtained by blending a urethane polymer with a specific ethylene- vinyl acetate copolymer, an oxazolidine latent crosslinking agent. CONSTITUTION:(A) 100pts.wt. urethane polymer (isocyanate group-containing polymer having preferably 1.5-4wt% terminal CNO group content) is blended with 1-50pts.wt., preferably 15-35pts.wt. ethylene-vinyl acetate copolymer having 20-80wt%, preferably 45-65wt% vinyl acetate content and (C) 5-50pts. wt., preferably 5-30pts.wt. oxazolidine or ketimine latent crosslinking agent [preferably oxazolidine crosslinking agent shown by the formula (R1 is 2-6C) aliphatic hydrocarbon; R2 and R3 are aliphatic, alicyclic or aromatic hydrocarbon)] to give the aimed sealant.

Racemization of 2-oxo-oxazolidine-4-carboxylic acid

Abstract: PURPOSE:To obtain an optically inactive DL-2-oxo-oxazolidine-4-carboxylic acid in high efficiency, by using a microbial strain capable of racemizing an optically active 2-oxo-oxazolidine-4-carboxylic acid to an optically inactive racemic compound. CONSTITUTION:An optically active 2-oxo-oxazolidine-4-carboxylic acid (hereinafter abbreviated as OOC) is treated and racemized with a treated product (e.g. culture liquid, separated microbial cell, etc.) of a microbial strain [e.g. Agrobacterium radiobacter AJ 2782 (ATCC 6466), Alcaligenes marshallii AJ 2147 (ATCC 21030), etc.] capable of racemizing an optically active OOC to optically inactive DL-OOC. L-serine can be accumulated in high efficiency even from DL-OOC by using an OOC-hydrolase-producing strain in combination with an OOC-racemizing microbial strain.

Manufacture of oxazolidines by the alkoxylation of imines

Abstract: N-substituted mono or bis-oxazolidines may be manufactured by reacting an alkylene oxide at alkoxylating conditions with a mono-imine of the general formula: or a bis-imine of the general formula: The oxazolidine may thereafter be cleaved with water, preferably slightly acidified, to produce the monoethoxylated amine.

Oxazolidines. 1. Basic catalytic disproportionation of cyclohexanospiro-2-oxazolidines: Synthesis of N-substituted 4,5,6,7-tetrahydroindoles

Abstract: It has been shown that the basic catalytic disproportionation of cyclohexanospiro-2-oxazolidines in the presence of potassium hydroxide or sodium methylate leads to N-substituted 4,5,6,7-tetrahydroindoles with a yield of up to 73% The influence of the character of substituents at the nitrogen atom of oxazolidine on the course of the reaction has been established

Process for preparing binders for cathodically depositable coatings

Abstract: The invention relates to a process for preparing binder combinations for cathodically electrodepositable coatings which, to improve the deposition characteristics, the bath stability and the film properties, contain an addition component based on compounds containing oxazolidine groups. The invention further relates to the use of selected compounds containing oxazolidine groups as addition component, in particular for increasing the film thicknesses achievable in electrodeposition on the workpiece connected as a cathode. The addition component (B), which is added in amounts of 3-20% to a cationic, film-forming resin, consists of oxazolidine compounds obtained by ring closure with carbonyl compounds from secondary amines of the groups (B1) reaction products of primary (poly)amines with monoepoxy compounds and/or di- or polyepoxy compounds whose epoxy groups may or may not have been reacted in proportion with other epoxide-reactive compounds, or (B2) addition products of primary alkanolamines with compounds having one or more CH2=CH-CO- groups, or (B3) reaction products of oxazolidine compounds of the groups (B1) and (B2) which contain hydroxyl groups with or without secondary amino groups, possibly after reaction of the secondary amino groups with monoepoxy compounds, and with di- or polyisocyanates.

Use of Chiral 1,3‐Oxazolidine‐2‐thiones in the Diastereoselective Synthesis of Aldols.

Abstract: A useful diastereoselective synthesis of aldols using chiral 3-acyl-1,3-oxazlidine-2-thiones, (1), (4), (7), and (9), is reported and its application to the synthesis of a chiral azetidinone (11) is described.