Showing papers on "Pulmonary diffusion published in 1973"
TL;DR: Findings suggest a common pathogenetic mechanism, and disordered cellular immune reactions directed primarily against the liver could affect other organs as a result of cross antigenicity.
189 citations
TL;DR: It is concluded that pulmonary fibrosis is common in rheumatoid disease and should be regarded as an expected manifestation, rather than an unusual complication, of the systemic process connoted by the term rheumatism.
147 citations
TL;DR: It is concluded that the variations in the level of lung inflation lead to a reduction in the available diffusion capacity by as much as 50 to 75 percent as compared to the values obtained on completely unfolded lungs.
93 citations
5 citations
TL;DR: Of eight patients undergoing pulmonary physiologic testing before and 24 hours after a restricted dose of ethiodized oil, one patient who received 10 ml or 0.255 ml/kg demonstrated decline in arterial oxygen pressure and pulmonary diffusion capacity associated with an x-ray film appearance of pulmonary oil embolization.
Abstract: Of eight patients undergoing pulmonary physiologic testing before and 24 hours after a restricted dose of ethiodized oil, one patient who received 10 ml or 0.255 ml/kg demonstrated decline in arterial oxygen pressure and pulmonary diffusion capacity associated with an x-ray film appearance of pulmonary oil embolization. There was no deterioration of pulmonary function in seven patients, who received less than 0.225 ml/kg of this substance. Of 12 patients whose chest films were evaluated for oil embolization 24 hours after lymphangiography, nine receiving less than 0.253 ml/kg demonstrated no oil embolization, whereas three receiving 0.292 ml/kg or more did develop embolization. Satisfactory lymphangiograms have been obtained with doses as low as 0.15 ml/kg. No deterioration of pulmonary function has occurred with doses of less than 0.25 ml/kg.
4 citations
TL;DR: Pulmonary diffusion was studied in 10 patients with diffuse lung disease and a decreased diffusing capacity for carbon monoxide, as measured by the single-breath method, making it possible to identify patients with a l...
Abstract: Pulmonary diffusion was studied using both oxygen and carbon monoxide in 10 patients with diffuse lung disease and a decreased diffusing capacity for carbon monoxide, as measured by the single-breath method. A new method for measuring diffusing capacity for oxygen during short-term hypoxia on exercise was used in 6 patients in whom the alveolar-arterial oxygen gradient due to mismatching of ventilation with perfusion and right-left shunt was minimal during short-term hypoxia at rest. In 4 patients with alveolar-arterial oxygen gradients of 10 mm Hg or more in similar circumstances, a diffusing capacity for oxygen was not measured. The values for diffusing capacities for oxygen and carbon dioxide agreed well in the 6 patients in whom comparisons were made. The low values of diffusing capacity for carbon monoxide in the other 4 patients were considered to be due to abnormal distribution of ventilation. The new method for measuring diffusing capacity for oxygen makes it possible to identify patients with a l...
1 citations
TL;DR: Late autotransplanted lungs suffered a mild reduction of lung compliance and lung volume and a moderate decrease of the diffusion capacity as compared with control values for the left lungs in normal dogs; however, none of these changes are statistically significant because of the wide variation of function of the left lung innormal dogs.