Showing papers on "Triphenyl phosphate published in 1980"
25 citations
TL;DR: Mono- and di-phenyl phosphates were more effective inhibitors than triphenyl phosphate, and deoxycholate decreased these inhibitory effects, and the results are interpreted in terms of inhibitor and de oxygencholate interactions with the enzyme.
Abstract: Inhibition of rat liver microsomal glucose-6-phosphatase (D-glucose-6-phosphate phosphohydrolase, EC 3.1.3.9) by orthophosphate and organophosphate esters was examined at pH 6.0 and 7.5 with and without enzyme pretreatment with 0.2% (w/v) deoxycholate. Inhibition by orthophosphate and monoethyl phosphate was competitive with respect to glucose-6-P while inhibition by mono- and di-phenyl phosphate was of the mixed type. Monoalkyl phosphates were more effective inhibitors than the analogous di- and tri-alkyl phosphates and deoxycholate potentiated the inhibitory effects. Mono- and di-phenyl phosphates were more effective inhibitors than triphenyl phosphate, and deoxycholate decreased these inhibitory effects. The results are interpreted in terms of inhibitor and deoxycholate interactions with the enzyme.
3 citations
TL;DR: In this article, an analytical method was developed for determining residue of phosphoric acid triesters (tri-n-butyl phosphate, tris (2-chloroethyl) phosphate, tri-namyl phosphate and triphenyl phosphate) in fish, sea sediment and sea water.
Abstract: An analytical method was developed for determining residue of phosphoric acid triesters (tri-n-butyl phosphate, tris (2-chloroethyl) phosphate, tri-n-amyl phosphate, tris (2, 3-dichloropropyl) phosphate, triphenyl phosphate, tris (2-butoxyethyl) phosphate, tricresyl phosphate, tris (2, 3-dibromopropyl) phosphate, tris (4-tert-butylphenyl) phosphate in fish, sea sediment and sea water. Phosphoric acid triesters were extracted from these materials with acetonitrile and methylene chloride. After n-hexane-acetonitrile partition, the extract was cleaned up by activated charcoal column chromatography, followed by extraction with conc. sulfuric acid, washing with 0.5N sodium hydroxide solution, and finally Florisil minicolumn chromatography. The purified extracts were analyzed with a gas chromatograph equipped with a flame photometric detector (P-filter) and with a gas chromatograph-mass spectrometer. The separation on gas chromatography was found to be good with 10% OV-1 on Chromosorb W experiments (AW-DMCS) and 5% FFAP on Gas Chrom Q. Throughout the present method, the recoveries of phosphoric acid triesters were in the range of 60-95%, and the detection limits (fish) were approximately 1-5μg/kg.
3 citations
Patent•
03 Jun 1980
TL;DR: In this article, the authors proposed a tubular product made of a resin composition composed of (a) 100 parts by weight of polybutylene terephthalate, (b) 1-100 parts of a rubber copolymer copolymized with a vinyl monomer, (c) 0-30 parts of an acid ester plasticizer, pref. triphenyl phosphate, and (d) 0 -100 part of a block copolyester ether elastomer.
Abstract: PURPOSE:To provide a tubular product having excellent light resistance, oxidation resistance, and impact strength, made of a composition composed of polybutylene terephthalate, a specific rubbery copolymer, a phosphoric ester plasticizer, and a polyether ester elastomer. CONSTITUTION:A tubular product made of a resin composition composed of (A) 100 parts by weight of polybutylene terephthalate, (B) 1-100 parts of a rubbery copolymer copolymerized with a vinyl monomer, (C) 0-30 parts of a phosphoric acid ester plasticizer, pref. triphenyl phosphate, and (D) 0-100 parts of a block copolyester ether elastomer composed of (a) a polyester wherein the content of polyalkylene terephthalate unit is >=60mol%, and (b) a poly(alkyleneoxide) glycol having a molecular weight of 400-6,000, wherein the weight ratio of (b)/(a)+(b) is 10-80wt%.
1 citations