Showing papers on "Wieland–Miescher ketone published in 2013"
TL;DR: In this article, the authors used a silica-gel supported binam-derived prolinamides for the intramolecular and intermolecular aldol reaction under solvent-free conditions using conventional magnetic stirring.
36 citations
TL;DR: In this article, a simple chiral primary amine catalyzed efficient and practical protocol for the large-scale synthesis of Wieland-Miescher and Hajos-Parrish ketones as well as their analogues is described.
Abstract: This article describes a simple chiral primary amine catalyzed efficient and practical protocol for the large-scale synthesis of Wieland–Miescher and Hajos–Parrish ketones as well as their analogues.
29 citations
NIIT1
TL;DR: Wieland-Miescher ketone 4 was synthesized using L-proline catalyst in the ionic liquid medium via non-selective conjugated addition reaction followed by an enantioselective intermolecular Aldol condensation reaction of triketone 3 intermediate.
Abstract: Wieland–Miescher ketone 4 was synthesised using L-proline catalyst in the ionic liquid medium via non-selective conjugated addition reaction followed by an enantioselective intermolecular Aldol condensation reaction of triketone 3 intermediate. Short reaction time, recycling of the catalyst, good yield and selectivity are major outcomes of this proposed protocol.
6 citations