Showing papers on "Withania somnifera published in 1975"
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TL;DR: In this article, seven steroidal lactones of the withanolide series have been isolated as minor constituents of the leaves of Withania somnifera Dun (Solanaceae) along with the major component withaferin A. The new compounds are: 27-hydroxywithanolide D(4β,20α,27-trihydroxy-1-oxo-5β,6β-epoxy-20 R,22 R -witha-2,24-dienolide) (11a ), 14α-hydroxwith
49 citations
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TL;DR: Two new steroidal lactones of the withanolide type, isolated from Withania somnifera Dun (Solanaceae), are characterized by the unusual presence of a C-23 hydroxy-group.
Abstract: Two new steroidal lactones of the withanolide type, isolated from Withania somnifera Dun (Solanaceae), are characterized by the unusual presence of a C-23 hydroxy-group. Withanolide Q (1a) is (22S,23R)-17α,23,27-trihydroxy-1-oxowitha-2,5,24-trienolide and withanolide R (2a) is (22S,23R)-6α,7α-epoxy-5α,23-dihydroxy-1-oxowitha-2,24-dienolide.
16 citations