Showing papers on "Zung Self-Rating Depression Scale published in 1999"
TL;DR: Hypericum extract was more effective at reducing Hamilton depression scores than placebo and at least as effective as 100 mg imipramine daily in the treatment of moderate depression and patients tolerate hypericum extracts much better than they do tricyclics and therefore by improving patients' compliance hypericum extract are promising drugs for long term treatment.
Abstract: Objectives: To assess the efficacy and safety of hypericum extract (STEI 300, Steiner Arzneimittel, Berlin) compared with imipramine and placebo in patients in primary care with a current episode of moderate depression. Design: Randomised, double blind, multicentre, parallel group trial for 8 weeks. Setting: Trained panel of 18 general practitioners from four German states: Bavaria, Berlin, Rhineland Palatinate, and Saxony. Participants: 263 patients (66 men, 197 women) with moderate depression according to ICD-10 (international classification of diseases, 10th revision) codes F32.1 and F33.1. Interventions: 1050 mg hypericum extract (350 mg three times daily), 100 mg imipramine (50 mg, 25 mg, and 25 mg daily), or placebo three times daily. Main outcome measures: Change from baseline score on the 17 item version of the Hamilton depression scale, the Hamilton anxiety scale, the clinical global impressions scale, Zung9s self rating depression scale, and SF-36, and adverse events profile. Results: Hypericum extract was more effective at reducing Hamilton depression scores than placebo and as effective as imipramine (mean −15.4 (SD 8.1), −12.1 (7.4), and −14.2 (7.3) respectively). Comparable results were found for Hamilton anxiety and clinical global impressions scales and were most pronounced for the Zung self rating depression scale. Quality of life was more improved in the standardised mental component scale of the SF-36 with both active treatments than with placebo but in the physical component scale was improved only by hypericum extract compared with placebo. The rate of adverse events with hypericum extract was in the range of the placebo group but lower than that of the imipramine group (0.5, 0.6, and 1.2 events per patient respectively). Conclusions: At an average dose of 350 mg three times daily hypericum extract was more effective than placebo and at least as effective as 100 mg imipramine daily in the treatment of moderate depression. Treatment with hypericum extract is safe and improves quality of life. Key messages Hypericum extract (STEI 300) was effective after 4, 6 and 8 weeks of treatment in patients with moderate depression Simultaneous analysis confirmed hypericum extract to be at least as efficacious as imipramine 100 mg daily after eight weeks of treatment Besides better antidepressive efficacy both hypericum extract and imipramine improved quality of life Patients tolerate hypericum extracts much better than they do tricyclics and therefore by improving patients9 compliance hypericum extracts are promising drugs for long term treatment
207 citations
TL;DR: There is evidence that burnout may be a clinical entity with pathological stress reaction features related to the inability in finding pleasure from work, and it seems that there may be two distinct types of burnout syndromes, of which the one comprising the majority of nurses has little or no common features with depression.
Abstract: Objective:There is evidence that burnout may be a clinical entity with pathological stress reaction features related to the inability in finding pleasure from work. The purpose of this study was to investigate the relationship between burnout and depression.Methods:The study took place in the general hospital AHEPA of Thessaloniki. All members of the nursing staff (in total 368 subjects) took part. The protocol was self-reported and anonymous, in order to obtain as valid data as possible and included the Maslach Burnout Inventory (MBI) to assess the level of burnout, the Eysenck Personality Questionnaire (EPQ) to assess personality traits, and the Zung Self-Rating Depression Scale to assess depressive symptomatology.Results:The analysis revealed a weak but significant relationship between burnout and depression.Conclusions:Depression is a pervasive disorder that affects almost every aspect of the patient's life. On the contrary, burnout is, by definition, a syndrome restricted to the patient's professiona...
79 citations
TL;DR: The results indicate that the THI depression scale is valid for use not only in epidemiological surveys but also in monitoring the severity of the depressive state.
Abstract: Content and Cross Validity of the Todai Health Index Depression Scale in Relation to the Center for Epidemiologic Studies Depression Scale and the Zung Self-rating Depression Scale: Tomoyuki KAWADA, et al. Department of Public Health, Gunma University School of Medicine—The validity of the Todai Health Index (THI) depression scale was tested with outpatient data by comparing with a clinical diagnosis based on the DSM III-R criteria of major depression. The cross validity of the Japanese versions of the CES-D score and SDS index were also tested in comparison with the THI scale scores of survey data from Japanese female students. The main results obtained were as follows: 1) The sensitivity, specificity, positive predictive value and negative predictive value of the THI depression scale were 0.91, 0.84, 0.86 and 0.89, respectively, and were satisfactory for identifying clinical cases of depression. 2) The CES-D score and the SDS index showed a high correlation with the THI scale scores, especially with the depression scale of THI. The coefficients of correlation for the THI depression scale and the CES-D score or SDS index were 0.727 and 0.715, respectively. The partial coefficients of correlation for the THI depression scale and the CES-D score or SDS index, when the variances of all other scale scores of the THI were kept constant, were 0.528 and 0.536, respectively. 3) Factor analysis was used to compare SDS and CES-D with 12 THI scales. SDS was related mainly to the psychological complaints and partly related to the physical symptoms. The results indicate that the THI depression scale is valid for use not only in epidemiological surveys but also in monitoring the severity of the depressive state.
27 citations
Journal Article•
TL;DR: The findings demonstrate the usefulness of the Zung Self-Rating Depression Scale for schizophrenics, however, due to findings of mixed reliability, caution should be exercised when using the SDS for these patients.
Abstract: Objective : This study was performed to provide psychometric data concerning the Zung Self-Rating Depression Scale (SDS) when administered to schizophrenics. Methods : The subjects were 110 schizophrenic inpatients (50 females and 60 males) who were diagnosed according to the DSM-IV criteria for schizophrenia. Informed consent was obtained from all subjects. Results : 1) Cronbach's alpha for the SDS was .81, and reached the acceptable range for internal consistency. 2) Test-retest reliability coefficient for the total SDS was comparatively high (Spearman's ρ=.87, p<.001, N=19), but those for SDS items revealed variability among items. 3) The mean total SDS score for the 15 patients with depression was significantly different from the group of patients without depression. 4) None of the 20 items or total SDS was significantly correlated with extra- pyramidal symptoms. Conclusions : Overall, the findings demonstrate the usefulness of the SDS for schizophrenics. However, due to findings of mixed reliability, caution should be exercised when using the SDS for these patients. J. Med. Invest. 46 : 75-78, 1999
12 citations
TL;DR: The Zung self‐rating depression scale (SDS) was applied to renal failure patients who were introduced to haemodialysis in the Nagoya Daini Red Cross Hospital, Nagoya, Japan.
Abstract: In the present study we applied the Zung self-rating depression scale (SDS) to 19 renal failure patients who were introduced to haemodialysis in the Nagoya Daini Red Cross Hospital, Nagoya, Japan. The patients were divided into two groups: the emergent introduction (EI) group, who underwent unanticipated and sudden introduction to haemodialysis, and the ordinary introduction (OI) group, who experienced a more systematic introduction to haemodialysis following recommendation by medical specialists. The patients' Zung SDS responses were collected twice, just before and 2 weeks after haemodialysis introduction. The total SDS score of the EI group was significantly higher than that of the OI group, both before and after haemodialysis introduction. The total SDS scores for the EI and OI groups were significantly reduced after haemodialysis introduction. The SDS scores for the EI group were significantly higher in the mood of depression and cognitive symptoms categories, both before and after haemodyalysis introduction. Before introduction, SDS scores of the EI group were significantly higher in the categories of motor and vegetative symptoms. The SDS scores for vegetative symptoms in the EI group significantly decreased after introduction to haemodialysis. These results suggest that haemodialytic excretion of uremic toxins helps to reduce SDS scores.
12 citations