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A.C. Dianoux
Researcher at Centre national de la recherche scientifique
Publications - 13
Citations - 464
A.C. Dianoux is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: ATP–ADP translocase & Mitochondrion. The author has an hindex of 9, co-authored 13 publications receiving 460 citations.
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Journal ArticleDOI
The mitochondrial ADP/ATP carrier: Structural, physiological and pathological aspects
C. Fiore,Véronique Trézéguet,A. Le Saux,Pierre Roux,Christine Schwimmer,A.C. Dianoux,Florence Noël,G.J-M. Lauquin,Gérard Brandolin,Pierre V. Vignais +9 more
TL;DR: The fluorometric approach, using the tryptophanyl residues of the yeast carrier as intrinsic fluorescence probes, was combined to a mutagenesis approach to elucidate the ADP/ATP transport mechanism at the molecular level to develop a method to quantify the carrier protein in muscular biopsies.
Journal ArticleDOI
Étude d'un lysozyme pauvre en cystine et en tryptophane: Le lysozyme de blanc d'oeuf d'oie
A.C. Dianoux,Pierre Jollès +1 more
TL;DR: Goose egg-white lysozyme was obtained in a chromatographically pure state; its amino acid composition was established and the terminal amino acids were determined, and it represents an interesting example in the study of the relationship between the structure and activity of lysozymes.
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A covalent tandem dimer of the mitochondrial ADP/ATP carrier is functional in vivo
Véronique Trézéguet,Agnès Le Saux,Claudine David,Céline Gourdet,C. Fiore,A.C. Dianoux,Gérard Brandolin,Guy J.-M. Lauquin +7 more
TL;DR: The results support the idea of a minimal dimeric functional organization of the Ancp in the mitochondrial membrane and can suggest that TMS 1 of one monomer and TMS 6 of the other monomer in the native dimer are very close to each other.
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Two distinct regions of the yeast mitochondrial ADP/ATP carrier are photolabeled by a new ADP analogue: 2-azido-3'-O-naphthoyl-[beta-32P]ADP. Identification of the binding segments by mass spectrometry.
A.C. Dianoux,Florence Noël,C. Fiore,Trézéguet,Kieffer S,Michel Jaquinod,Guy J.-M. Lauquin,Gérard Brandolin +7 more
TL;DR: Plausible models of organization of the nucleotide binding site(s) of the carrier involving the two regions specifically labeled by 2-azido-N-[(32)P]ADP are proposed.
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The O2− generating oxidase of B lymphocytes: Epstein-Barr virus-immortalized B lymphocytes as a tool for the identification of defective components of the oxidase in chronic granulamatous disease
Françoise Morel,L. Cohen Tanugi Cholley,Gérard Brandolin,A.C. Dianoux,Cécile Martel,P. Champelovier,J.M. Seigneurin,François P,Bost M,Pierre V. Vignais +9 more
TL;DR: Activation of neutrophil oxidase in an heterologous cell-free system, using human neutrophIL membranes and EBV-B lymphocyte cytosol from healthy and CGD patients, combined with immunoblotting investigations of the cytosolic activating factors p47 and p67 involved in O2- production, suggests that neutrophils andEBV- B lymphocytes possess similar complements of cytOSolic factors p67 and p47.