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A. H. Zwinderman
Researcher at Leiden University
Publications - 56
Citations - 1749
A. H. Zwinderman is an academic researcher from Leiden University. The author has contributed to research in topics: Coronary artery disease & Pravastatin. The author has an hindex of 20, co-authored 52 publications receiving 1713 citations.
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Journal ArticleDOI
Magnetic resonance imaging during dobutamine stress for detection and localization of coronary artery disease. Quantitative wall motion analysis using a modification of the centerline method.
F. P. Van Rugge,E. E. van der Wall,S. J. Spanjersberg,A. de Roos,Niels A. A. Matheijssen,A. H. Zwinderman,P. R. M. Van Dijkman,J.H.C. Reiber,A. V. G. Bruschke +8 more
TL;DR: Dobutamine MRI is an accurate method for detection and localization of myocardial ischemia and may emerge as a new noninvasive approach for evaluation of patients with known or suspected coronary artery disease.
Journal ArticleDOI
Biophysical properties of the normal-sized aorta in patients with Marfan syndrome: evaluation with MR flow mapping.
M. Groenink,A. de Roos,B.J.M. Mulder,B. Verbeeten,Janneke Timmermans,A. H. Zwinderman,J. A. E. Spaan,E. E. van der Wall +7 more
TL;DR: MR imaging reveals abnormal biophysical properties of the normal-sized aorta in patients with Marfan syndrome, which is relevant for evaluating disease progression and treatment options.
Journal ArticleDOI
Biological and chemical monitoring of occupational exposure to ethylene oxide.
Ad D. Tates,T. Grummt,Margareta Törnqvist,P. B. Farmer,F.J. van Dam,H. van Mossel,H.M. Schoemaker,S Osterman-Golkar,Ch. Uebel,Y.S. Tang,A. H. Zwinderman,Adayapalam T. Natarajan,Lars Ehrenberg +12 more
TL;DR: These results are the first demonstration of mutation induction in man by ethylene oxide, and the relative sensitivity of endpoints for detection of EtO exposure was HOEtVal adducts greater than SCEs more than chromosomal aberrations greater than micronuclei greater than HPRT mutants.
Journal ArticleDOI
Effect of the stromelysin-1 promoter on efficacy of pravastatin in coronary atherosclerosis and restenosis.
M. De Maat,J. W. Jukema,J. W. Jukema,Shu Ye,Shu Ye,A. H. Zwinderman,Payman Hanifi Moghaddam,Payman Hanifi Moghaddam,Marian Beekman,Marian Beekman,J.J.P. Kastelein,AJ van Boven,AJ van Boven,A. V. G. Bruschke,A. V. G. Bruschke,S. E. Humphries,C. Kluft,C. Kluft,A. M. Henney,A. M. Henney +19 more
TL;DR: This study suggests that the stomelysin-1 promoter polymorphism confers a genotype-specific response to medication in determining clinical event-free survival and the risk for symptom-driven repeat angioplasty.
Journal ArticleDOI
The Asp9 Asn mutation in the lipoprotein lipase gene is associated with increased progression of coronary atherosclerosis. REGRESS Study Group, Interuniversity Cardiology Institute, Utrecht, The Netherlands. Regression Growth Evaluation Statin Study.
Joop Jukema,AJ van Boven,Björn E. Groenemeijer,A. H. Zwinderman,J.H.C. Reiber,A. V. G. Bruschke,J.A. Henneman,G.P. Molhoek,T. Bruin,Hans Jansen,E. Gagne,Michael R. Hayden,J.J.P. Kastelein +12 more
TL;DR: This study shows that heterozygosity for a mutation in the LPL gene, which causes only subtle changes in fasting plasma lipids, may promote the progression of coronary atherosclerosis and diminish clinical event-free survival.