A
A. John Morgan
Researcher at Cardiff University
Publications - 52
Citations - 2297
A. John Morgan is an academic researcher from Cardiff University. The author has contributed to research in topics: Lumbricus rubellus & Earthworm. The author has an hindex of 27, co-authored 52 publications receiving 2146 citations. Previous affiliations of A. John Morgan include Imperial College London & King's College London.
Papers
More filters
Journal ArticleDOI
Microevolution and ecotoxicology of metals in invertebrates.
TL;DR: The evidence for the existence of genetically differentiated, metal-resistant, invertebrate populations is surveyed and some of the molecular mechanisms underpinning the adaptations are described, urging that biomarker studies should work toward assimilating and exploiting these biological realities.
Journal ArticleDOI
'Systems toxicology' approach identifies coordinated metabolic responses to copper in a terrestrial non-model invertebrate, the earthworm Lumbricus rubellus
Jacob G. Bundy,Jasmin K Sidhu,Faisal Rana,David J. Spurgeon,Claus Svendsen,Jodie F Wren,Jodie F Wren,Stephen R. Stürzenbaum,A. John Morgan,Peter Kille +9 more
TL;DR: Multiple post-genomic techniques can be combined to provide mechanistic information about the toxic effects of chemical contaminants, even for non-model organisms with few additional mechanistic toxicological data.
Journal ArticleDOI
Metal ion trafficking in earthworms. Identification of a cadmium-specific metallothionein.
TL;DR: This study fully characterizes the major metal-binding protein in earthworms, namely the two isoforms of metallothionein, namely wMT-2 and its role in cadmium detoxification through sequestration and compartmentalization is discussed.
Journal ArticleDOI
Cadmium detoxification in earthworms: from genes to cells
TL;DR: A detailed dissection of the genetic, molecular, and cellular basis of a sophisticated pathway that facilitates the uptake, accumulation, transport, and excretion of cadmium is provided.
Journal ArticleDOI
Transcriptome profiling of developmental and xenobiotic responses in a keystone soil animal, the oligochaete annelid Lumbricus rubellus
Jennifer Owen,B Ann Hedley,Claus Svendsen,Jodie F Wren,Martijs J. Jonker,Peter K. Hankard,Linsey J Lister,Stephen R. Stürzenbaum,A. John Morgan,David J. Spurgeon,Mark Blaxter,Peter Kille +11 more
TL;DR: L. rubellus has a complex response to contaminant exposure, but this can be efficiently analysed using molecular methods, revealing unique response profiles for different classes of effector.