A. Tejera

TL;DR: A multivariable model is proposed based on the findings to classify embryos according to their probability of implantation and it is proposed that the image acquisition and time-lapse analysis system makes it possible to determine exact timing of embryo cleavages in a clinical setting.

TL;DR: The AOA with calcium ionophore treatment improved fertilization rate and quality of the embryos, and was found to be an effective method for AOA in this patient with a low fertilization rates after previous ICSI treatment.

TL;DR: O from individual embryos revealed significant differences, mainly close to the time of transfer, when OC pattern was associated with successful implantation, therefore, measuring the OC pattern of human embryos culture up to 72 hours could be used to select the embryo with best developmental potential.

TL;DR: The sample size is the largest ever described that provides consistent information about the normal distribution of embryo developmental timings and allows accuracy and objectivity when defining the basis of embryo development within a clinic.

TL;DR: This study suggests that OE exhibits a global transcriptomic effect on oocytes of patients in OE, independently if they come from an affected or unaffected ovary and alters key biological processes and molecular functions related to steroid metabolism, response to oxidative stress and cell growth regulation, which reduce oocyte quality.