A
Abhishek Kumar Singh
Researcher at Amity University
Publications - 95
Citations - 1575
Abhishek Kumar Singh is an academic researcher from Amity University. The author has contributed to research in topics: Oxidative stress & Autophagy. The author has an hindex of 19, co-authored 84 publications receiving 1175 citations. Previous affiliations of Abhishek Kumar Singh include Indian Institute of Toxicology Research & Council of Scientific and Industrial Research.
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Chitosan/TiO2 composite membrane improves proliferation and survival of L929 fibroblast cells: Application in wound dressing and skin regeneration
TL;DR: The data confirmed that CS/TiO2 (0.25%) membrane improved the growth, survival and functional integrity of fibroblasts, and exerted antibacterial activity which may be utilized as potential dressing materials.
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Neuroprotection Through Rapamycin-Induced Activation of Autophagy and PI3K/Akt1/mTOR/CREB Signaling Against Amyloid-β-Induced Oxidative Stress, Synaptic/Neurotransmission Dysfunction, and Neurodegeneration in Adult Rats.
Abhishek Kumar Singh,Mahendra Kashyap,Vinay Kumar Tripathi,Sandeep Singh,Geetika Garg,Syed Ibrahim Rizvi +5 more
TL;DR: It is demonstrated that autophagy can be an integrated part of pro-survival (PI3K/Akt1/mTOR/CREB) signaling and autophagic activation restores the oxidative defense mechanism(s), neurodegenerative damages, and maintains the integrity of synapse and neurotransmission in rat model of AD.
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Antiaging Effect of Metformin on Brain in Naturally Aged and Accelerated Senescence Model of Rat.
TL;DR: It is confirmed that metformin restores the antioxidant status and improves healthy brain aging through the activation of autophagy and reduction in inflammation.
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Fisetin as a caloric restriction mimetic protects rat brain against aging induced oxidative stress, apoptosis and neurodegeneration.
TL;DR: It is suggested that fisetin supplementation may provide neuroprotection against aging‐induced oxidative stress, apoptotic cell death, neuro‐inflammation, and neurodegeneration in rat brain.
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Nano-titanium dioxide induces genotoxicity and apoptosis in human lung cancer cell line, A549.
Ritesh K. Srivastava,Qamar Rahman,Mahendra Kashyap,Mahendra Kashyap,Abhishek Kumar Singh,Abhishek Kumar Singh,Girish Kumar Jain,Girish Kumar Jain,Sadaf Jahan,Sadaf Jahan,Mohtashim Lohani,M Lantow,A. B. Pant,A. B. Pant +13 more
TL;DR: Data indicate that nano-TiO2 induces oxidative stress, genotoxicity and apoptosis in human lung cancer cell line, A549, and identifies the mechanisms involved in TiO2 NP-induced changes in A549 cells.