Abrams John S

TL;DR: The general strategy for preparing a large panel of anti-mouse and human cytokine monoclonal antibodies (mAb) and setting up cytokine immunoassays and this review outlines the general strategy followed.

TL;DR: DCIR represents a novel surface molecule expressed by Ag presenting cells, and of potential importance in regulation of DC function, and was expressed on DC, monocytes, macrophages, B lymphocytes, and granulocytes, but not detected on NK and T cells.

TL;DR: It is suggested that eosinophils are attracted to the airway during the late-phase allergic reaction and that IL-5 may produce changes in airway eos inophil density and promote the release of granular proteins to cause airway injury.

TL;DR: In vitro data demonstrate that iSC cells produce IL‐6 in response to PC12 cell coculture and to stimuli that induce IL‐8 production in the hematopoietic lineage and the induction of IL‐ 6 message distal to a crush injury suggests another mechanism by which Schwann cells facilitate peripheral nerve regeneration.

TL;DR: The results indicate that the differences in expression and biological activities of IL-4 and IL-13 on T cells may have consequences for the relative roles of these cytokines in the immune response.