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Achilles Dugaiczyk
Researcher at University of California, Riverside
Publications - 31
Citations - 1630
Achilles Dugaiczyk is an academic researcher from University of California, Riverside. The author has contributed to research in topics: Gene & Alu element. The author has an hindex of 21, co-authored 31 publications receiving 1595 citations. Previous affiliations of Achilles Dugaiczyk include Baylor College of Medicine.
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Nucleotide sequence and the encoded amino acids of human serum albumin mRNA
TL;DR: The complete nucleotide sequence of human serum albumin mRNA has been determined from recombinant cDNA clones and from a primer-extended cDNA synthesis on the mRNA template, which verifies and refines the repeating homology in the triple-domain structure of the serumalbumin molecule.
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Molecular structure of the human albumin gene is revealed by nucleotide sequence within q11-22 of chromosome 4.
Phillip P. Minghetti,Duane E. Ruffner,Wun-Jing Kuang,O. E. Dennison,J. W. Hawkins,W. G. Beattie,Achilles Dugaiczyk +6 more
TL;DR: The human albumin gene spans 16,961 nucleotides from the putative "Cap" site to the first poly(A) addition site and appears to have been recently invaded by Alu repetitive sequences.
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Structure, polymorphism, and novel repeated DNA elements revealed by a complete sequence of the human alpha-fetoprotein gene.
TL;DR: The human alpha-fetoprotein gene spans 19,489 base pairs from the putative "Cap" site to the polyadenylation site, and from phylogenetic evidence, it appears that Alu elements were inserted into the alpha- Fetop Protein gene at some time postdating the mammalian radiation 85 million years ago.
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Origin and phylogenetic distribution of Alu DNA repeats: irreversible events in the evolution of primates.
TL;DR: The data suggest that new Alu elements arise in unique, irreversible events, in a mechanism that seems to preclude precise excision and loss, and submit that only irreversible and taxonomically relevant events are at the molecular basis of evolution.
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The Ovalbumin Gene: Cloning of the Natural Gene
Savio L. C. Woo,Achilles Dugaiczyk,Ming-Jer Tsai,Eugene C. Lai,James F. Catterall,Bert W. O'Malley +5 more
TL;DR: The intervening sequences were found to be unique chicken DNA sequences, and appeared to be transcribed in their entireties during gene expression, and like the structural gene sequences, the expression of the intervening sequences is also inducible by steroid hormones.