A
Adam Brufsky
Researcher at University of Pittsburgh
Publications - 538
Citations - 33601
Adam Brufsky is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 74, co-authored 460 publications receiving 27570 citations. Previous affiliations of Adam Brufsky include MedStar Washington Hospital Center & Kaiser Permanente.
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Journal ArticleDOI
Impaired glucose metabolism in patients with diabetes, prediabetes, and obesity is associated with severe COVID-19.
Stephen M. Smith,Avinash Boppana,Julie A. Traupman,Enrique Unson,Daniel A. Maddock,Kathy Chao,David P. Dobesh,Adam Brufsky,Ruth I Connor +8 more
TL;DR: The association of dysregulated glucose metabolism and severe COVID‐19 suggests that SARS‐CoV‐2 pathogenesis involves a novel interplay with glucose metabolism, which is critical for understanding disease pathogenesis and developing therapies.
Journal ArticleDOI
Phase II trial of high‐dose, intermittent calcitriol (1,25 dihydroxyvitamin D3) and dexamethasone in androgen‐independent prostate cancer
TL;DR: The combination of high‐dose, intermittent calcitriol (1,25 dihydroxyvitamin D3) plus dexamethasone was studied based on evidence that dexamETHasone potentiates the antitumor effects of calcitriols and ameliorates hypercalcemia.
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Sunitinib Plus Paclitaxel Versus Bevacizumab Plus Paclitaxel for First-Line Treatment of Patients With Advanced Breast Cancer: A Phase III, Randomized, Open-Label Trial
Nicholas J. Robert,Mansoor N. Saleh,Devchand Paul,Daniele Generali,Laurent Gressot,Mehmet Sitki Copur,Adam Brufsky,Susan E. Minton,Jeffrey K. Giguere,John W. Smith,Paul Richards,Diana Gernhardt,Xin Huang,K. F. Liau,Kenneth A. Kern,John M. Davis +15 more
TL;DR: The sunitinib-paclitaxel regimen evaluated in this study was clinically inferior to the bevacizumab- paclitaxe regimen and is not a recommended treatment option for patients with advanced breast cancer.
Journal ArticleDOI
Comprehensive transcript analysis in small quantities of mRNA by SAGE-Lite
David G. Peters,Elisa Heidrich O'Hare,Robert E. Ferrell,Amin B. Kassam,Howard Yonas,Adam Brufsky +5 more
TL;DR: A modification of SAGE is developed that allows detailed global analysis of gene expression in extremely small quantities of tissue or cultured cells and is called 'SAGE-Lite', which allows simple and rapid isolation of long cDNAs from short SAGE sequence tags.
Journal ArticleDOI
Influence of patient and treatment factors on adherence to adjuvant endocrine therapy in breast cancer.
Catherine M. Bender,Amanda L. Gentry,Adam Brufsky,Frances E. Casillo,Susan M. Cohen,Meredith M. Dailey,Heidi S. Donovan,Jacqueline Dunbar-Jacob,Rachel C. Jankowitz,Margaret Rosenzweig,Paula R. Sherwood,Susan M. Sereika +11 more
TL;DR: Women with breast cancer may be at risk for nonadherence to prescribed endocrine therapy if they experience depression or anxiety and symptoms prior to initiating therapy, and oncology nurses should be alert to women who are depressed or anxious or who are experiencing symptoms.