Adam P. Bress

TL;DR: Among young adults, those with elevated blood pressure, stage 1 hypertension, and stage 2 hypertension before age 40 years, as defined by the blood pressure classification in the 2017 American College of Cardiology/American Heart Association (ACC/AHA) guidelines, had significantly higher risk for subsequent cardiovascular disease events compared with those with normal blood pressure before age40 years.

TL;DR: This retrospective analysis demonstrated that more severe LA LGE is associated with increased MACCE risk, driven primarily by increased risk of stroke or TIA.

TL;DR: In this simulation study, intensive systolic blood‐pressure control prevented cardiovascular disease events and prolonged life and did so at levels below common willingness‐to‐pay thresholds per QALY, regardless of whether benefits were reduced after 5 years or persisted for the patient's remaining lifetime.

TL;DR: Among both the overall U.S. population and adults with treated hypertension, the percentage meeting SPRINT eligibility criteria increased with older age, was higher among males than females, and was higheramong non-Hispanic whites compared with non- Hispanic blacks or Hispanics.

TL;DR: Sacubitril-valsartan may be a cost-effective treatment option depending on the willingness-to-pay threshold and future investigations should incorporate real-world evidence with sacubitrill-valsartsartan to further inform decision making.