Adrian Minty

TL;DR: The demonstration that p73 is monoallelically expressed supports the notion that it is a candidate gene in neuroblastoma and proposes that the disregulation of p73 contributes to tumorigenesis and that p53-related proteins operate in a network of developmental and cell cycle controls.

TL;DR: Recombinant IL-13 protein inhibits inflammatory cytokine production induced by lipopolysaccharide in human peripheral blood monocytes, and synergizes with IL-2 in regulating interferon-γ synthesis in large granular lymphocytes.

TL;DR: Analysis of codon usage in these coding sequences in different vertebrate species indicates two tendencies: increases in bias toward the use of G and C in the third codon position in paralogous comparisons, and in orthologous comparisons.

TL;DR: These regulatory regions upstream of the cap site of the human cardiac actin gene show remarkably high sequence conservation with the equivalent regions of the mouse and chick genes and there is an evolutionarily conserved repeated motif that may be important in the transcriptional regulation of actin and other contractile protein genes.

TL;DR: It is shown here that p73alpha, but not p73beta, can be covalently modified by SUMO-1, and is more rapidly degraded by the proteasome than unmodified p73, although SUMo-1 modification is not required for p73 degradation.