A
Afanas'ev Mv
Researcher at Peninsular Malaysia
Publications - 8
Citations - 227
Afanas'ev Mv is an academic researcher from Peninsular Malaysia. The author has contributed to research in topics: Mycobacterium tuberculosis & rpoB. The author has an hindex of 5, co-authored 8 publications receiving 220 citations.
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Molecular characteristics of rifampicin- and isoniazid-resistant Mycobacterium tuberculosis isolates from the Russian Federation
Afanas'ev Mv,L.N. Ikryannikova,Elena N. Ilina,Sergey Sidorenko,Kuz'min Av,Elena Larionova,Smirnova Tg,Larisa Chernousova,Eugeny Yu. Kamaev,Sergey N. Skorniakov,Vladimir N. Kinsht,Andrey G. Cherednichenko,Vadim M. Govorun +12 more
TL;DR: The new MALDI-TOF MS-based method may be used for rapid and accurate monitoring of the spread of drug resistance in Mycobacterium tuberculosis clinical isolates.
Journal ArticleDOI
Comparative Genomic Analysis of Mycobacterium tuberculosis Drug Resistant Strains from Russia
Elena N. Ilina,Egor Shitikov,L.N. Ikryannikova,Dmitry G. Alekseev,Dmitri E. Kamashev,Maja V. Malakhova,Tatjana V. Parfenova,Afanas'ev Mv,Dmitry S. Ischenko,Nikolai A. Bazaleev,Tatjana G. Smirnova,Elena Larionova,Larisa Chernousova,Alexey V. Beletsky,A. V. Mardanov,Nikolai V. Ravin,Konstantin G. Skryabin,Vadim M. Govorun +17 more
TL;DR: This work sequenced three genomes of Russian MTB strains of different phenotypes – drug susceptible, MDR and XDR and confirmed drug resistant status of these isolates that harbored almost all known drug-resistance associated mutations.
Journal ArticleDOI
Mass spectrometry based methods for the discrimination and typing of mycobacteria.
Egor Shitikov,Elena N. Ilina,Larisa Chernousova,Alexandra D. Borovskaya,I. Rukin,Afanas'ev Mv,Smirnova Tg,A. Vorobyeva,Elena Larionova,S. Andreevskaya,Markus Kostrzewa,Vadim M. Govorun +11 more
TL;DR: MALDI-ToF MS has potential as a rapid and reproducible platform for the identification and typing of Mycobacterium species and was developed and validated and matched completely to classical spoligotyping data.
Journal ArticleDOI
Molecular typing of Mycobacterium tuberculosis circulated in Moscow, Russian Federation
Afanas'ev Mv,L.N. Ikryannikova,Elena N. Ilina,Kuz'min Av,Elena Larionova,Smirnova Tg,Larisa Chernousova,V. M. Govorun +7 more
TL;DR: Comparison of the 24-VNTR locus typing and spoligotyping data with revealed resistance-associated mutation allows us to make a suggestion that the active transmission of MDR strains and the independent appearance of drug resistance during chemotherapy occurred in the studied population simultaneously.
Journal ArticleDOI
Mass-spectrometry based minisequencing method for the rapid detection of drug resistance in Mycobacterium tuberculosis
L.N. Ikryannikova,Afanas'ev Mv,T. A. Akopian,Elena N. Ilina,Kuz'min Av,Elena Larionova,Smirnova Tg,Larisa Chernousova,Vadim M. Govorun +8 more
TL;DR: It is deduced that 91% of RIF-resistant and 94% of INH-resistant strains can be identified using the technique suggested and the approach is rapid, reliable and allows to reveal the drug resistance of M. tuberculosis strains within 12 h after sample isolation.