L
Larisa Chernousova
Researcher at Russian Academy
Publications - 53
Citations - 1118
Larisa Chernousova is an academic researcher from Russian Academy. The author has contributed to research in topics: Mycobacterium tuberculosis & Tuberculosis. The author has an hindex of 16, co-authored 50 publications receiving 978 citations.
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Journal ArticleDOI
Identification of Rifampin-Resistant Mycobacterium tuberculosis Strains by Hybridization, PCR, and Ligase Detection Reaction on Oligonucleotide Microchips
V. M. Mikhailovich,Sergey A. Lapa,D. A. Gryadunov,Alexander Y. Sobolev,Boris N. Strizhkov,Nikolai Chernyh,Olga Skotnikova,Olga Irtuganova,Arkadii Moroz,Vitalii Litvinov,Mikhail Vladimirskii,Mikhail Perelman,Larisa Chernousova,Vladislav V. Erokhin,Alexander S. Zasedatelev,Andrei D. Mirzabekov,Andrei D. Mirzabekov +16 more
TL;DR: Three new molecular approaches were developed to identify drug-resistant strains of Mycobacterium tuberculosis using biochips with oligonucleotides immobilized in polyacrylamide gel pads, significantly faster than traditional bacteriological methods.
Journal ArticleDOI
Extensive Drug Resistance Acquired During Treatment of Multidrug-Resistant Tuberculosis
J. Peter Cegielski,Tracy Dalton,Martin Yagui,Wanpen Wattanaamornkiet,Grigory V. Volchenkov,Laura E. Via,Martie van der Walt,Thelma E. Tupasi,Sarah Smith,Ronel Odendaal,Vaira Leimane,Charlotte Kvasnovsky,Tatiana Kuznetsova,Ekaterina V. Kurbatova,Tiina Kummik,Liga Kuksa,Kai Kliiman,Elena V. Kiryanova,Hee Jin Kim,Chang Ki Kim,Boris Y. Kazennyy,Ruwen Jou,Wei-Lun Huang,Julia Ershova,Vladislav V. Erokhin,Lois Diem,Carmen Contreras,Sang Nae Cho,Larisa Chernousova,Michael P. Chen,Janice Campos Caoili,Jaime Bayona,Somsak Akksilp,Gloria Yale Calahuanca,Melanie Wolfgang,Piret Viiklepp,Irina A. Vasilieva,Allison Taylor,Kathrine R. Tan,Carmen Suarez,Ingrida Sture,Tatiana Somova,Tatyana G. Smirnova,Erika Sigman,Girts Skenders,Wanlaya Sitti,Isdore Chola Shamputa,Vija Riekstina,Kristine Rose Pua,M. Therese,C. Perez,Seung Kyu Park,Inga Norvaisha,Evgenia S. Nemtsova,Seonyeong Min,Beverly Metchock,Klavdia Levina,Yung-Chao Lei,Jong Seok Lee,Elena E. Larionova,Joey Lancaster,Doosoo Jeon,Oswaldo Jave,Tatiana Khorosheva,Soo Hee Hwang,Angela Song-En Huang,M. Tarcela Gler,Gunta Dravniece,Seokyong Eum,Olga V. Demikhova,Irina Degtyareva,Manfred Danilovits,Anda Cirula,E.K. Cho,Ying Cai,Jeanette Brand,Cesar Bonilla,Clifton E. Barry,Luis Asencios,Sofia N. Andreevskaya,Rattanawadee Akksilp +80 more
TL;DR: Treatment of MDR tuberculosis involves substantial risk of acquired resistance to SLDs, increasing as baseline drug resistance increases, and the risk was significantly lower in programs documented by the GLC to meet specific standards.
Journal ArticleDOI
Evaluation of hybridisation on oligonucleotide microarrays for analysis of drug-resistant Mycobacterium tuberculosis
Dmitry A. Gryadunov,V. M. Mikhailovich,Sergey A. Lapa,N. Roudinskii,M. Y. Donnikov,S. V. Pan'kov,O. V. Markova,Alexey V. Kuz'min,Larisa Chernousova,Skotnikova Oi,Moroz Am,Alexander S. Zasedatelev,Mirzabekov Ad +12 more
TL;DR: The sensitivity and specificity of the developed method were comparable with those of standard bacteriological testing of M. tuberculosisDrug-resistant strains of Mycobacterium tuberculosis are identified using biochips immobilised in polyacrylamide gel pads.
Journal ArticleDOI
Molecular characteristics of rifampicin- and isoniazid-resistant Mycobacterium tuberculosis isolates from the Russian Federation
Afanas'ev Mv,L.N. Ikryannikova,Elena N. Ilina,Sergey Sidorenko,Kuz'min Av,Elena Larionova,Smirnova Tg,Larisa Chernousova,Eugeny Yu. Kamaev,Sergey N. Skorniakov,Vladimir N. Kinsht,Andrey G. Cherednichenko,Vadim M. Govorun +12 more
TL;DR: The new MALDI-TOF MS-based method may be used for rapid and accurate monitoring of the spread of drug resistance in Mycobacterium tuberculosis clinical isolates.
Journal ArticleDOI
Multidrug-Resistant Tuberculosis Treatment Outcomes in Relation to Treatment and Initial Versus Acquired Second-Line Drug Resistance
J. Peter Cegielski,Ekaterina V. Kurbatova,Martie van der Walt,Jeannette Brand,Julia Ershova,Thelma E. Tupasi,Janice Campos Caoili,Tracy Dalton,Carmen Contreras,Martin Yagui,Jaime Bayona,Charlotte Kvasnovsky,Vaira Leimane,Liga Kuksa,Michael P. Chen,Laura E. Via,Soo Hee Hwang,Melanie Wolfgang,Grigory V. Volchenkov,Tatiana Somova,Sarah Smith,Somsak Akksilp,Wanpen Wattanaamornkiet,Hee Jin Kim,Chang Ki Kim,Boris Y. Kazennyy,Tatiana Khorosheva,Kai Kliiman,Piret Viiklepp,Ruwen Jou,Angela Song-En Huang,Irina Vasilyeva,Olga V. Demikhova,Global Petts Investigators,Joey Lancaster,Ronel Odendaal,Lois Diem,Therese C Perez,Tarcela Gler,Kathrine R. Tan,Cesar Bonilla,Oswaldo Jave,Luis Asencios,Gloria Yale,Carmen Suarez,Allison Taylor Walker,Inga Norvaisha,Girts Skenders,Ingrida Sture,Vija Riekstina,Andra Cirule,Erika Sigman,Sang Nae Cho,Ying Cai,Seokyong Eum,Jongmin Lee,Seung-kyu Park,Doosoo Jeon,Isdore Chola Shamputa,Beverly Metchock,Tatiana Kuznetsova,Rattanawadee Akksilp,Wanlaya Sitti,Jirapan Inyapong,Elena V. Kiryanova,Irina Degtyareva,Evgenia S. Nemtsova,Klavdia Levina,Manfred Danilovits,Tiina Kummik,Yung-Chao Lei,Wei-Lun Huang,Vladislav V. Erokhin,Larisa Chernousova,Sofia N. Andreevskaya,Elena E. Larionova,Tatyana G. Smirnova +76 more
TL;DR: Increasing drug resistance was associated in a logical stepwise manner with poor treatment outcomes and acquired resistance was worse than initial resistance to the same drugs.