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Agnieszka Dabrowska
Researcher at Jagiellonian University
Publications - 15
Citations - 365
Agnieszka Dabrowska is an academic researcher from Jagiellonian University. The author has contributed to research in topics: Virus & NS3. The author has an hindex of 7, co-authored 15 publications receiving 180 citations.
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Journal ArticleDOI
The SARS-CoV-2 ORF10 is not essential in vitro or in vivo in humans.
Katarzyna Pancer,Aleksandra Milewska,Katarzyna Owczarek,Agnieszka Dabrowska,Michał Kowalski,Paweł P. Łabaj,Wojciech Branicki,Marek Sanak,Krzysztof Pyrc +8 more
TL;DR: It appears that the ORF10 protein is not essential in humans and should not be treated as the protein-coding gene, and the genome annotations should be amended.
Journal ArticleDOI
Membrane Protein of Human Coronavirus NL63 Is Responsible for Interaction with the Adhesion Receptor.
Antonina Naskalska,Agnieszka Dabrowska,Artur Szczepanski,Aleksandra Milewska,Krzysztof Jasik,Krzysztof Pyrc +5 more
TL;DR: The M protein is shown to be an important player during early stages of HCoV-NL63 infection and that the concerted action of the two proteins (M and S) is a prerequisite for effective infection.
Journal ArticleDOI
HTCC as a Polymeric Inhibitor of SARS-CoV-2 and MERS-CoV.
Aleksandra Milewska,Ying Chi,Artur Szczepanski,Emilia Barreto-Duran,Agnieszka Dabrowska,Pawel Botwina,Magdalena Obłoza,Kevin Liu,Dan Liu,Xiling Guo,Yiyue Ge,Li Jingxin,Lunbiao Cui,Marek Ochman,Maciej Urlik,Sylwia Rodziewicz-Motowidło,Fengcai Zhu,Fengcai Zhu,Krzysztof Szczubiałka,Maria Nowakowska,Krzysztof Pyrc +20 more
TL;DR: The antiviral activity of an HTCC compound, previously developed by us, is described, which may be used as a potential inhibitor of currently circulating highly pathogenic coronaviruses—SARS- coV-2 and MERS-CoV.
Journal ArticleDOI
Replication of Severe Acute Respiratory Syndrome Coronavirus 2 in Human Respiratory Epithelium.
Aleksandra Milewska,Anna Kula-Pacurar,Jakub Wadas,Agnieszka Suder,Artur Szczepanski,Agnieszka Dabrowska,Katarzyna Owczarek,Alessandro Marcello,Marek Ochman,Tomasz Stacel,Zenon Rajfur,Marek Sanak,Pawel Labaj,Wojciech Branicki,Krzysztof Pyrc +14 more
TL;DR: It is shown that fully differentiated human airway epithelium cultures constitute an excellent model to study infection with the novel human coronavirus SARS-CoV-2, and efficient replication of the virus in the tissue, with maximal replication at 2 days postinfection.
Journal ArticleDOI
Novel coronavirus-like particles targeting cells lining the respiratory tract
Antonina Naskalska,Agnieszka Dabrowska,Paulina Nowak,Artur Szczepanski,Krzysztof Jasik,Aleksandra Milewska,Marek Ochman,Slawomir Zeglen,Zenon Rajfur,Krzysztof Pyrc +9 more
TL;DR: It is shown that these nanoparticles may deliver cargo and selectively transduce cells expressing the ACE2 protein such as ciliated cells of the respiratory tract and serve as a delivery platform.