A
Ahmad Ahmadzadeh
Researcher at Ahvaz Jundishapur University of Medical Sciences
Publications - 66
Citations - 787
Ahmad Ahmadzadeh is an academic researcher from Ahvaz Jundishapur University of Medical Sciences. The author has contributed to research in topics: Leukemia & Myeloid leukemia. The author has an hindex of 11, co-authored 66 publications receiving 622 citations.
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Journal ArticleDOI
Targeting PI3K/AKT/mTOR network for treatment of leukemia.
Jessika Bertacchini,Nazanin Heidari,Laura Mediani,Silvano Capitani,Mohammad Shahjahani,Ahmad Ahmadzadeh,Najmaldin Saki +6 more
TL;DR: Modulation of miRNA can be used as a novel therapeutic approach to regulate the PI3K/Akt/mTOR pathway and may have pro-apoptotic and antiproliferative effects on hematological malignancies.
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Wnt/β-catenin signaling in bone marrow niche
TL;DR: The ability to modulate the Wnt pathway either positively or negatively may be of therapeutic relevance, and the controlled activation of Wnt signaling might allow us to enhance stem and progenitor cell activity when regeneration is needed.
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Mesenchymal stem cells as a double-edged sword in suppression or progression of solid tumor cells
TL;DR: The role of a number of pathways, including IL-6/STAT3 pathway, has been indicated in controlling the interaction between MSCs and tumor cells, and other mechanisms by which M SCs can control the tumor cells are not clear yet.
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Molecular Regulation of Bone Marrow Metastasis in Prostate and Breast Cancer
Fakher Rahim,Saeideh Hajizamani,Esmaeil Mortaz,Ahmad Ahmadzadeh,Mohammad Shahjahani,Saeid Shahrabi,Najmaldin Saki +6 more
TL;DR: The molecular regulation of bone marrow metastasis in prostate and breast cancers is highlighted to provide important therapeutic targets for treatment of these patients.
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Significance of oncogenes and tumor suppressor genes in AML prognosis.
TL;DR: Proto-oncogenes and tumor suppressor genes, which are important in normal development of myeloid cells, are involved in the regulation of cell cycle and apoptosis, undergo mutation in this type of leukemia, and are effective in prognosis of AML subtypes are reviewed.