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Ahmad Besaratinia
Researcher at University of Southern California
Publications - 75
Citations - 3906
Ahmad Besaratinia is an academic researcher from University of Southern California. The author has contributed to research in topics: DNA damage & DNA methylation. The author has an hindex of 30, co-authored 71 publications receiving 3402 citations. Previous affiliations of Ahmad Besaratinia include German Cancer Research Center & City of Hope National Medical Center.
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Mutations induced by ultraviolet light
TL;DR: It is shown that CPDs (rather than 6-4 photoproducts or other lesions) are responsible for the great majority of UVB-induced mutations and the role of DNA damage-tolerant DNA polymerases in UV lesion bypass and mutagenesis is discussed.
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UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer
TL;DR: The data implicate the CPD as the DNA lesion most strongly involved in human cancers induced by sunlight, including non-melanoma and melanoma skin cancers.
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A review of mechanisms of acrylamide carcinogenicity.
TL;DR: The present review is a synopsis of research on the known and hypothetical modes of action of acrylamide of relevance for carcinogenesis with special emphasis on DNA adduct-targeted mutagenesis.
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Genotoxicity of Acrylamide and Glycidamide
TL;DR: The mutagenicity of acrylamide in human and mouse cells is based on the capacity of its epoxide metabolite glycidamide to form DNA adducts.
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Mutational spectra of human cancer
TL;DR: Evidence that can be used to reconstruct the etiology of human cancers from mutations found in tumors is summarized to produce mutational spectra similar to those in TP53 but have unveiled a previously unrecognized common G to C transversion mutation signature at GpA dinucleotides in breast cancers and several other cancers.