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Aidan I. Brown
Researcher at University of California, San Diego
Publications - 50
Citations - 574
Aidan I. Brown is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Biology & Heterocyst. The author has an hindex of 11, co-authored 41 publications receiving 332 citations. Previous affiliations of Aidan I. Brown include Ryerson University & Dalhousie University.
Papers
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Journal ArticleDOI
Theory of nonequilibrium free energy transduction by molecular machines
Aidan I. Brown,David A. Sivak +1 more
TL;DR: In this paper, the authors review central questions in BiMolecular Machines' performance as free energy transducers, outline theoretical and modeling approaches to understand these questions, identify both physical limits on their operational characteristics and design principles for improving performance, and discuss emerging areas of research.
Journal ArticleDOI
Getting around the cell: physical transport in the intracellular world.
TL;DR: The interplay of diffusion, molecular motors, and flows supports the intracellular transport needs that underlie a broad variety of biological phenomena.
Journal ArticleDOI
Theory of Nonequilibrium Free Energy Transduction by Molecular Machines.
Aidan I. Brown,David A. Sivak +1 more
TL;DR: Central questions in biomolecular machines performance as free energy transducers are reviewed, theoretical and modeling approaches are outlined, and both physical limits on their operational characteristics and design principles for improving performance are identified.
Journal ArticleDOI
High-resolution and high-accuracy topographic and transcriptional maps of the nucleosome barrier.
Zhijie Chen,Ronen Gabizon,Aidan I. Brown,Antony Lee,Aixin Song,César Díaz-Celis,Craig D. Kaplan,Elena F. Koslover,Tingting Yao,Carlos Bustamante +9 more
TL;DR: Topographic and transcriptional maps of canonical, H2A.Z, and monoubiquitinated H2B (uH2B) nucleosomes are obtained at near base-pair resolution and accuracy and suggest a mechanism for selective control of gene expression.
Journal ArticleDOI
Mitochondrial Fission and Fusion Dynamics Generate Efficient, Robust, and Evenly Distributed Network Topologies in Budding Yeast Cells
Matheus P. Viana,Aidan I. Brown,Irina A. Mueller,Claire Goul,Elena F. Koslover,Susanne M. Rafelski +5 more
TL;DR: Mitochondrial fission and fusion combine to regulate the underlying topology of mitochondrial networks, which may independently impact cell function.