A
Aifeng Zou
Researcher at China Pharmaceutical University
Publications - 14
Citations - 1409
Aifeng Zou is an academic researcher from China Pharmaceutical University. The author has contributed to research in topics: Micelle & Glucosamine. The author has an hindex of 7, co-authored 14 publications receiving 1102 citations.
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Journal ArticleDOI
DDSolver: An Add-In Program for Modeling and Comparison of Drug Dissolution Profiles
TL;DR: The development of a software program, called DDSolver, for facilitating the assessment of similarity between drug dissolution data and to establish a model library for fitting dissolution data using a nonlinear optimization method is described.
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Synthesis and characterization of low-toxic amphiphilic chitosan derivatives and their application as micelle carrier for antitumor drug.
TL;DR: A series of safety studies revealed that the PTX-loaded OGC micelles had advantages over the commercially available injectable preparation of PTX (Taxol((R))), in terms of low toxicity levels and increased tolerated dose.
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Somatostatin receptor-mediated tumor-targeting drug delivery using octreotide-PEG-deoxycholic acid conjugate-modified N-deoxycholic acid-O, N-hydroxyethylation chitosan micelles
Meirong Huo,Aifeng Zou,Chengli Yao,Yong Zhang,Jianping Zhou,Jing Wang,Qinnv Zhu,Jing Li,Qiang Zhang +8 more
TL;DR: In vivo investigation of micelles on nude mice bearing MCF-7 cancer xenografts confirmed that OPD-DAHC micells possessed much higher tumor-targeting capacity than the DAHC control and exhibited enhanced anti-tumor efficacy and decreased systemic toxicity.
Journal ArticleDOI
Formation, microstructure, biodistribution and absence of toxicity of polymeric micelles formed by N-octyl-N,O-carboxymethyl chitosan
TL;DR: In this article, N-octyl-N,O-carboxymethyl chitosans (Octyl-CM-Chitosan) with different molecular weights and degrees of alkylation were synthesized.
Journal ArticleDOI
Octreotide-Modified N-Octyl-O, N-Carboxymethyl Chitosan Micelles as Potential Carriers for Targeted Antitumor Drug Delivery
Aifeng Zou,Meirong Huo,Yong Zhang,Jianping Zhou,Xiaoqiang Yin,Chengli Yao,Qinnv Zhu,Min Zhang,Jinshan Ren,Qiang Zhang +9 more
TL;DR: OCC-OCT micelles may be a promising intracellular targeting carrier for efficient delivery of antitumor drugs into tumor cells by increasing the uptake of DOX in MCF-7 cells.