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Aishwarya Acharya
Researcher at Tata Institute of Fundamental Research
Publications - 2
Citations - 33
Aishwarya Acharya is an academic researcher from Tata Institute of Fundamental Research. The author has contributed to research in topics: Anabolism & Citric acid cycle. The author has an hindex of 2, co-authored 2 publications receiving 19 citations. Previous affiliations of Aishwarya Acharya include Max Planck Society.
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Journal ArticleDOI
Anabolic SIRT4 Exerts Retrograde Control over TORC1 Signaling by Glutamine Sparing in the Mitochondria.
Eisha Shaw,Manasi Talwadekar,Zeenat Rashida,Nitya Mohan,Aishwarya Acharya,Subhash Khatri,Sunil Laxman,Ullas Kolthur-Seetharam +7 more
TL;DR: SIRT4 is established as key anabolic factor that activates TORC1 signaling and regulates lipogenesis, autophagy, and cell proliferation and conclusively shows that differential expression of SIRT4 during fed and fasted states is vital for coupling mitochondrial energetics and glutamine utilization with anabolic pathways.
Posted ContentDOI
Anabolic SIRT4 exerts retrograde control over TORC1 signalling by glutamine sparing in the mitochondria
Eisha Shaw,Manasi Talwadekar,Nitya Mohan,Aishwarya Acharya,Aishwarya Acharya,Ullas Kolthur-Seetharam +5 more
TL;DR: SIRT4 is established as key anabolic factor that activates TORC1 signalling and regulates lipogenesis, autophagy and cell proliferation and it is conclusively shown that differential expression of SIRT4 during fed and fasted states is vital for coupling mitochondrial energetics and glutamine utilization with anabolic pathways.