A
Akira Iwata
Researcher at Hokkaido University
Publications - 51
Citations - 1711
Akira Iwata is an academic researcher from Hokkaido University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 11, co-authored 42 publications receiving 1447 citations.
Papers
More filters
Journal ArticleDOI
Growth Phase-Dependent Variation in Protein Composition of the Escherichia coli Nucleoid
TL;DR: Using a quantitative Western blot method, this work has performed for the first time a systematic determination of the intracellular concentrations of 12 species of the nucleoid protein in E. coli, finding that changes in the composition of nucleoid-associated proteins in the stationary phase are accompanied by compaction of the genome DNA and silencing of the genomes functions.
Journal ArticleDOI
Amyloid β accumulation in axons after traumatic brain injury in humans
TL;DR: The results of this study indicate that damaged axons can serve as a target for antibodies selective for Aβ peptides, amyloid precursor protein (APP), and neurofilament (NF) proteins in brain-injured patients.
Journal ArticleDOI
Intracellular Concentrations of 65 Species of Transcription Factors with Known Regulatory Functions in Escherichia coli
Akira Ishihama,Akira Ishihama,Ayako Kori,Etsuko Koshio,Kayoko Yamada,Hiroto Maeda,Tomohiro Shimada,Hideki Makinoshima,Akira Iwata,Nobuyuki Fujita +9 more
TL;DR: The systematic search for the target promoters recognized by each sigma factor and each TF using the newly developed Genomic SELEX system and the promoter-specific (PS)-TF screening system for identification of the whole set of TFs involved in regulation of each promoter are described.
Journal ArticleDOI
Isolation from Tobacco Mosaic Virus-Infected Tobacco of a Solubilized Template-Specific RNA-Dependent RNA Polymerase Containing a 126K/183K Protein Heterodimer
Takato Watanabe,Takato Watanabe,Ayae Honda,Akira Iwata,Susumu Ueda,Tadaaki Hibi,Akira Ishihama +6 more
TL;DR: It is proposed that the TMV RNA polymerase for minus-strand RNA synthesis is composed of one molecule each of the 183- and 126-kDa proteins, possibly together with two or more host proteins.
Journal ArticleDOI
Genome-wide association study identifies 14 previously unreported susceptibility loci for adolescent idiopathic scoliosis in Japanese.
Ikuyo Kou,Nao Otomo,Kazuki Takeda,Yukihide Momozawa,Hsing Fang Lu,Michiaki Kubo,Yoichiro Kamatani,Yoji Ogura,Yohei Takahashi,Masahiro Nakajima,Shohei Minami,Koki Uno,Noriaki Kawakami,Manabu Ito,Ikuho Yonezawa,Kei Watanabe,Takashi Kaito,Haruhisa Yanagida,Hiroshi Taneichi,Katsumi Harimaya,Yuki Taniguchi,Hideki Shigematsu,Takahiro Iida,Satoru Demura,Ryo Sugawara,Nobuyuki Fujita,Mitsuru Yagi,Eijiro Okada,Naobumi Hosogane,Naobumi Hosogane,Katsuki Kono,Masaya Nakamura,Kazuhiro Chiba,Kazuhiro Chiba,Toshiaki Kotani,Tsuyoshi Sakuma,Tsutomu Akazawa,Teppei Suzuki,Kotaro Nishida,Kenichiro Kakutani,Taichi Tsuji,Hideki Sudo,Akira Iwata,Tatsuya Sato,Satoshi Inami,Morio Matsumoto,Chikashi Terao,Kota Watanabe,Shiro Ikegawa +48 more
TL;DR: The authors report GWAS followed by genome-wide meta-analysis in up to 79,211 Japanese individuals, identifying 20 genetic loci for AIS, including 14 of which were previously unreported, and perform in vitro validation for rs1978060.