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Alain Furber
Researcher at University of Angers
Publications - 67
Citations - 1304
Alain Furber is an academic researcher from University of Angers. The author has contributed to research in topics: Myocardial infarction & Ejection fraction. The author has an hindex of 20, co-authored 62 publications receiving 1208 citations. Previous affiliations of Alain Furber include Centre national de la recherche scientifique.
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Journal ArticleDOI
RISK and SAFE signaling pathway interactions in remote limb ischemic perconditioning in combination with local ischemic postconditioning
Sophie Tamareille,Victor Mateus,Nehmat Ghaboura,Julien Jeanneteau,Anne Croue,Daniel Henrion,Alain Furber,Fabrice Prunier +7 more
TL;DR: The combination of IPost and RIPer improved cardioprotection through the recruitment of the SAFE pathway, indicating that cross talk exists between the RISK and SAFE pathways.
Journal ArticleDOI
The RIPOST-MI study, assessing remote ischemic perconditioning alone or in combination with local ischemic postconditioning in ST-segment elevation myocardial infarction.
Fabrice Prunier,Denis Angoulvant,Christophe Saint Etienne,Emmanuelle Vermes,Martine Gilard,Christophe Piot,François Roubille,Meyer Elbaz,Michel Ovize,Loïc Bière,Julien Jeanneteau,Stéphane Delépine,Thomas Benard,Wissam Abi-Khalil,Alain Furber +14 more
TL;DR: Starting RIPer therapy immediately prior to revascularization was shown to reduce infarct size in STEMI patients, yet combining this therapy with an IPost strategy did not lead to further decrease in infarCT size.
Journal ArticleDOI
Diabetes mellitus abrogates erythropoietin-induced cardioprotection against ischemic-reperfusion injury by alteration of the RISK/GSK-3β signaling.
Nehmat Ghaboura,Sophie Tamareille,Pierre-Henri Ducluzeau,Linda Grimaud,Laurent Loufrani,Anne Croue,Yves Tourmen,Daniel Henrion,Alain Furber,Fabrice Prunier +9 more
TL;DR: Direct inhibition of GSK-3β may provide an alternative strategy to protect diabetic hearts against ischemia–reperfusion (I/R) injury through activation of the reperfusion injury salvage kinase (RISK) pathway.
Journal ArticleDOI
Role of hypoxia inducible factor-1α in remote limb ischemic preconditioning
Hussein Kalakech,Sophie Tamareille,Sandrine Pons,Sandrine Pons,Diane Godin-Ribuot,Diane Godin-Ribuot,Peter Carmeliet,Alain Furber,Valérie Martin,Valérie Martin,Alain Berdeaux,Alain Berdeaux,Bijan Ghaleh,Bijan Ghaleh,Fabrice Prunier +14 more
TL;DR: Results suggest that HIF-1α upregulation is unnecessary in acute RIPC, a feasible and attractive therapeutic procedure for heart protection against ischemia/reperfusion (I/R) injury.
Journal ArticleDOI
Apolipoprotein A-I Is a Potential Mediator of Remote Ischemic Preconditioning
Pierre Hibert,Delphine Prunier-Mirebeau,Olivia Beseme,Olivia Beseme,Olivia Beseme,Maggy Chwastyniak,Maggy Chwastyniak,Maggy Chwastyniak,Sophie Tamareille,Delphine Lamon,Alain Furber,Florence Pinet,Fabrice Prunier +12 more
TL;DR: The identification of RIPC-induced humoral mediators using a proteomic approach suggests that ApoA-I may be a protective blood-borne factor involved in the RIPC mechanism and recapitulated the cardioprotection offered by RIPC in rats.