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Alan L. Devonshire

Researcher at The Hertz Corporation

Publications -  115
Citations -  6115

Alan L. Devonshire is an academic researcher from The Hertz Corporation. The author has contributed to research in topics: Myzus persicae & Esterase. The author has an hindex of 43, co-authored 115 publications receiving 5836 citations. Previous affiliations of Alan L. Devonshire include University of Hertfordshire & Rothamsted Research.

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Molecular characterization of pyrethroid knockdown resistance (kdr) in the major malaria vector Anopheles gambiae s. s.

TL;DR: This work demonstrates that a modification of the voltage‐gated sodium channel protein recently shown to be associated with mutations of the para‐type sodium channel gene is present in certain strains of pyrethroid resistant A. gambiae, and describes a PCR‐based diagnostic test allowing its detection in the genome of single mosquitoes.
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Identification and characterization of mutations in housefly (Musca domestica) acetylcholinesterase involved in insecticide resistance

TL;DR: The baculovirus expression of wild-type and mutated housefly AChE proteins has confirmed that the mutations each confer relatively modest levels of insecticide insensitivity except the novel Gly-262-->Val mutation, which results in much stronger resistance (up to 100-fold) to certain compounds.
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Molecular evidence that insecticide resistance in peach-potato aphids (Myzus persicae Sulz.) results from amplification of an esterase gene.

TL;DR: Qualitative differences between restriction patterns in different clones of resistant aphids correlated with the presence or absence of a specific chromosome translocation and with production of E4 or FE4.
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Gene amplification and insecticide resistance.

TL;DR: In this paper, le mecanisme de resistance des insectes face aux substances toxiques, base on l'amplification des genes de resistance, is described and evaluated.
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A sodium channel point mutation is associated with resistance to DDT and pyrethroid insecticides in the peach-potato aphid, Myzus persicae (Sulzer) (Hemiptera: Aphididae).

TL;DR: These findings, and the linkage disequilibrium of the kdr mutation within clones overproducing the E4 esterase, have important implications for the evolution of resistance in this insect and for the use of pyrethroid sprays in the management of M. persicae populations in the field.