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Alan T. Mulgrew
Researcher at University of British Columbia
Publications - 23
Citations - 2025
Alan T. Mulgrew is an academic researcher from University of British Columbia. The author has contributed to research in topics: Obstructive sleep apnea & Sleep apnea. The author has an hindex of 17, co-authored 23 publications receiving 1888 citations. Previous affiliations of Alan T. Mulgrew include Bon Secours Hospital Tralee & Royal College of Surgeons in Ireland.
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Journal ArticleDOI
Diagnosis and Initial Management of Obstructive Sleep Apnea without Polysomnography: A Randomized Validation Study
TL;DR: In this paper, a computer algorithm based on analysis of oxygen saturation measured by pulse oximetry was used to determine the probability of obstructive sleep apnea in patients with high probability.
Journal ArticleDOI
Impact of continuous positive airway pressure therapy on blood pressure in patients with obstructive sleep apnea hypopnea: a meta-analysis of randomized controlled trials.
M. Alajmi,Alan T. Mulgrew,Joel Fox,W. Davidson,Michael Schulzer,E. Mak,C F Ryan,John A. Fleetham,P. Choi,Najib T. Ayas,Najib T. Ayas +10 more
TL;DR: The effects of CPAP were modest and not statistically significant; CPAP (compared to control) reduced systolic BP (SBP) by 1.38 mmHg; there was a trend for SBP reduction to be associated with CPAP compliance, and future randomized controlled trials in this area should potentially concentrate on these subgroups of patients.
Journal ArticleDOI
The impact of obstructive sleep apnea and daytime sleepiness on work limitation
Alan T. Mulgrew,C.F. Ryan,John A. Fleetham,Rupi Cheema,Nurit Fox,Mieke Koehoorn,J.M. FitzGerald,J.M. FitzGerald,Carlo A. Marra,Najib T. Ayas,Najib T. Ayas +10 more
TL;DR: There is a clear relationship between excessive sleepiness and decreased work productivity in a population referred for suspected sleep-disordered breathing and screening for sleepiness in the workplace has the potential to identify a reversible cause of low work productivity.
Journal ArticleDOI
Risk and severity of motor vehicle crashes in patients with obstructive sleep apnoea/hypopnoea
Alan T. Mulgrew,G Nasvadi,Arsalan Butt,Rupi Cheema,Nurit Fox,John A. Fleetham,C F Ryan,P Cooper,Najib T. Ayas,Najib T. Ayas +9 more
TL;DR: Patients with OSAH have increased rates of MVCs, and disproportionately increased rates Of motor vehicle crashes are associated with personal injury.
Journal ArticleDOI
Cathepsin B, L, and S Cleave and Inactivate Secretory Leucoprotease Inhibitor
Clifford C. Taggart,Gregory J. Lowe,Catherine M. Greene,Alan T. Mulgrew,Shane J. O'Neill,Rodney L. Levine,Noel G. McElvaney +6 more
TL;DR: Findings indicate the involvement of cathepsins in the diminution of the lung antiprotease screen possibly leading to lung destruction in emphysema.