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Alberto Abbruzzese
Researcher at Seconda Università degli Studi di Napoli
Publications - 148
Citations - 6304
Alberto Abbruzzese is an academic researcher from Seconda Università degli Studi di Napoli. The author has contributed to research in topics: Apoptosis & Hypusine. The author has an hindex of 46, co-authored 148 publications receiving 5978 citations. Previous affiliations of Alberto Abbruzzese include University of Naples Federico II & National Institutes of Health.
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Journal ArticleDOI
Molecular targets and oxidative stress biomarkers in hepatocellular carcinoma: an overview
Monica Marra,I. Sordelli,Angela Lombardi,Monica Lamberti,Luciano Tarantino,Aldo Giudice,Paola Stiuso,Alberto Abbruzzese,Rossella Sperlongano,Marina Accardo,Massimo Agresti,Michele Caraglia,Pasquale Sperlongano +12 more
TL;DR: The detection of molecular factors predictive of response to anti-cancer agents such as sorafenib and the identification of mechanisms of resistance toAnti- cancer agents may probably represent the direction to improve the treatment of HCC.
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Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism
Massimo Donadelli,Ilaria Dando,T Zaniboni,Chiara Costanzo,E. Dalla Pozza,Maria Teresa Scupoli,Aldo Scarpa,Silvia Zappavigna,M. Marra,Alberto Abbruzzese,Maurizio Bifulco,Michele Caraglia,Michela Palmieri +12 more
TL;DR: Findings support a key role of the ROS-dependent activation of an autophagic program in the synergistic growth inhibition induced by GEM/cannabinoid combination in human pancreatic cancer cells.
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Familial papillary thyroid microcarcinoma: a new clinical entity
Giovanni Lupoli,Giovanni Vitale,Michele Caraglia,M. R. Fittipaldi,Alberto Abbruzzese,Pierosandro Tagliaferri,Angelo Raffaele Bianco +6 more
TL;DR: The unfavourable behaviour in the familial form of papillary thyroid microcarcinoma suggests that radical treatment and careful follow-up are warranted.
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Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro.
Pierfrancesco Tassone,Pierosandro Tagliaferri,Caterina Viscomi,Camillo Palmieri,Michele Caraglia,Angelo D'Alessandro,E Galea,Ajay Goel,Alberto Abbruzzese,Clement Richard Boland,Salvatore Venuta +10 more
TL;DR: It is demonstrated that ZOL induces growth inhibition and apoptosis on PC cells and interferes with growth and survival pathways downstream to p21ras, which might be relevant for expanding application of BPs in cancer treatment.
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The translation elongation factor 1A in tumorigenesis, signal transduction and apoptosis: review article
TL;DR: This article summarizes the present knowledges on the several extra-translational roles of eEF1A also in order to understand as the protein synthesis regulatory mechanisms could offer tools for cancer intervention.