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Alberto Margonato

Researcher at Vita-Salute San Raffaele University

Publications -  281
Citations -  6866

Alberto Margonato is an academic researcher from Vita-Salute San Raffaele University. The author has contributed to research in topics: Heart failure & Coronary artery disease. The author has an hindex of 36, co-authored 266 publications receiving 6009 citations. Previous affiliations of Alberto Margonato include University of Milan & Università telematica San Raffaele.

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Erectile dysfunction prevalence, time of onset and association with risk factors in 300 consecutive patients with acute chest pain and angiographically documented coronary artery disease.

TL;DR: It is suggested that a significant proportion of patients with angiographically documented coronary artery disease have erectile dysfunction and that this latter condition may become evident prior to angina symptoms in almost 70% of cases.
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“Ultrasound Comet-Tail Images”: A Marker Of Pulmonary Edema: A Comparative Study With Wedge Pressure And Extravascular Lung Water

TL;DR: The presence and the number of comet-tail images provide reliable information on interstitial pulmonary edema, and ultrasonography represent an attractive, easy-to-use, bedside diagnostic tool for assessing cardiac function and pulmonary congestion.
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A randomized clinical trial of trimetazidine, a partial free fatty acid oxidation inhibitor, in patients with heart failure.

TL;DR: Long-term trimetazidine improves functional class and left ventricular function in patients with HF, which contrasts with the natural history of the disease, as shown by the decrease of EF in patients on standard HF therapy alone.
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Effects of metabolic modulation by trimetazidine on left ventricular function and phosphocreatine/adenosine triphosphate ratio in patients with heart failure.

TL;DR: Timetazidine improves functional class and LV function in patients with heart failure and is associated to the observed trimetazidine-induced increase in the PCr/ATP ratio, indicating preservation of the myocardial high-energy phosphate levels.
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Short- and long-term beneficial effects of trimetazidine in patients with diabetes and ischemic cardiomyopathy.

TL;DR: In a short series of patients with diabetes and ischemic cardiomyopathy, TMZ improved left ventricular function, symptoms, glucose metabolism, and endothelial function, and shifting energy substrate preference away from fatty acid metabolism and toward glucose metabolism by TMZ appears an effective adjunctive treatment.