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Aleksey V. Tolmachev
Researcher at Pacific Northwest National Laboratory
Publications - 56
Citations - 3379
Aleksey V. Tolmachev is an academic researcher from Pacific Northwest National Laboratory. The author has contributed to research in topics: Ion & Mass spectrometry. The author has an hindex of 36, co-authored 55 publications receiving 3104 citations. Previous affiliations of Aleksey V. Tolmachev include University of Nebraska Medical Center & Environmental Molecular Sciences Laboratory.
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Journal ArticleDOI
The ion funnel: theory, implementations, and applications.
TL;DR: Improvements in fundamental understanding of ion motion in ion funnels are reviewed, the evolution in its implementations that have brought the ion funnel to its current state of refinement, as well as applications of the ions funnel for purposes such as ion trapping, ion cooling, low pressure electrospray, and ion mobility spectrometry.
Journal ArticleDOI
High-sensitivity ion mobility spectrometry/mass spectrometry using electrodynamic ion funnel interfaces.
Keqi Tang,Alexandre A. Shvartsburg,Hak-No Lee,David C. Prior,Michael A. Buschbach,Fumin Li,Aleksey V. Tolmachev,Gordon A. Anderson,Richard D. Smith +8 more
TL;DR: The overall sensitivity of the present E SI-IMS-MS system is comparable to that of commercial ESI-MS, which should make IMS-MS suitable for analyses of complex mixtures with ultrahigh sensitivity and exceptional throughput.
Journal ArticleDOI
Design and Implementation of a New Electrodynamic Ion Funnel
Taeman Kim,Aleksey V. Tolmachev,Richard Harkewicz,David C. Prior,Gordon A. Anderson,Harold R. Udseth,Richard D. Smith,Thomas H. Bailey,Sergey Rakov,Jean H. Futrell +9 more
TL;DR: The new electrodynamic ion funnel displays a significant improvement in low-mass transmission (m/z >200) and sensitivity compared to previous designs and can be operated in two different modes, allowing fragile noncovalent complexes (as well as generally undesired adducts) to be transmitted.
Journal ArticleDOI
Characterization of an improved electrodynamic ion funnel interface for electrospray ionization mass spectrometry.
Scott A. Shaffer,Aleksey V. Tolmachev,David C. Prior,Gordon A. Anderson,Harold R. Udseth,Richard D. Smith +5 more
TL;DR: An improved electrodynamic ion funnel for ion focusing at high pressure (> 1 Torr) has been developed for a triple quadrupole mass spectrometer and its performance compared with that of an earlier prototype previously reported.
Journal ArticleDOI
Ultra-High Resolution Ion Mobility Separations Utilizing Traveling Waves in a 13 m Serpentine Path Length Structures for Lossless Ion Manipulations Module.
Liulin Deng,Yehia M. Ibrahim,Ahmed M. Hamid,Sandilya V. B. Garimella,Ian K. Webb,Xueyun Zheng,Spencer A. Prost,Jeremy A. Sandoval,Randolph V. Norheim,Gordon A. Anderson,Aleksey V. Tolmachev,Erin S. Baker,Richard D. Smith +12 more
TL;DR: The development and initial evaluation of a 13 m path length Structures for Lossless Manipulations (SLIM) module for achieving high resolution separations using traveling waves (TW) with ion mobility (IM) spectrometry and it provides a foundation for the development of much higher resolution SLIM devices based upon both considerably longer path lengths and multipass designs.