Alena Gerlinde Thiele

TL;DR: To evaluate the experiences of families with very young children aged 1 to 7 years (inclusive) with type 1 diabetes using day‐and‐night hybrid closed‐loop insulin delivery, a large number of families opted for the day-and-night approach.

TL;DR: Unrestricted home use of day-and-night closed-loop in very young children with type 1 diabetes is feasible and safe and the use of diluted insulin during closed- loop does not provide additional benefits compared with standard strength insulin.

TL;DR: PKU patients under a relaxed diet are at risk of an insufficient nutrient supply, if they have first no substitution with AAM, second a protein supply less than 0.5 g per kg body weight from AAM or third a total protein supplyLess than 120% of the recommendations.

TL;DR: Continuous care for adult PKU patients in a specialized outpatient clinic is successful, leading to good to satisfactory metabolic control and social outcomes.

TL;DR: The liberalized diet under BH4 seems to jeopardize the quality of patients' nutrition, and these patients require close follow-up and special nutrition education to minimize the risk for imbalanced diet and nutrient deficiencies.