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Alessandro Allegra

Researcher at University of Messina

Publications -  252
Citations -  4642

Alessandro Allegra is an academic researcher from University of Messina. The author has contributed to research in topics: Medicine & Multiple myeloma. The author has an hindex of 31, co-authored 214 publications receiving 3629 citations.

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Circulating microRNAs: New biomarkers in diagnosis, prognosis and treatment of cancer (Review)

TL;DR: The role of circulating miRNAs could be particularly relevant in the context of neoplastic diseases, and the profiling of alterations in circulating miRNA that may signal a predisposition to cancer, could also be a therapeutic target in these patients.
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Erythropoietin protects against brain ischemic injury by inhibition of nitric oxide formation.

TL;DR: In vivo recombinant human erythropoietin effects on brain ischemic injury could be due to inhibition of NO overproduction, as indicated by reduction in nitrite and nitrate in the hippocampus, as observed after ischemia.
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Anticancer Activity of Curcumin and Its Analogues: Preclinical and Clinical Studies

TL;DR: This review provides an overview of the recent research conducted to overcome the problems with the bioavailability of curcumin, and of the preclinical and clinical studies that have reported success in combinatorial strategies couplingCurcumin with other treatments.
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Relationship between plasma leptin levels and the tumor necrosis factor-α system in obese subjects

TL;DR: The results are consistent with the hypothesis that the TNFα system could be involved in the regulation of plasma leptin concentrations in obese subjects.
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Inflammatory and Anti-Inflammatory Equilibrium, Proliferative and Antiproliferative Balance: The Role of Cytokines in Multiple Myeloma.

TL;DR: The association between MM and inflammatory cytokines appears to be inadequate, and other functions, such as pro-proliferative or antiproliferative effects, can assume the role of cytokines in the genesis and progression of MM.